We have mapped a global network of virus–host protein interactions by purification of the
complete set of human papillomavirus (HPV) proteins in multiple cell lines followed by mass …

Persistent high-risk genus human Alphapapillomavirus (HPV) infections cause nearly every
cervical carcinoma and a subset of tumors in the oropharyngeal tract. During the decades …

Recent next-generation sequencing studies have generated a comprehensive overview of
the genomic landscape of human papillomavirus (HPV)–associated cancers. This review …

Cervical cancer (CC) that is caused by high-risk human papillomavirus (HPV) remains a
significant public health problem worldwide. HPV integration sites can be silent or actively …

Persistent infection with a subset of “high oncogenic risk” human papillomaviruses (HPVs)
can promote the development of cancer. In these cancers, the extrachromosomal viral …

Integration of human papillomavirus (HPV) DNA into the human genome is a reputed key
driver of cervical cancer. However, the effects of HPV integration on chromatin structural …

High-risk HPV E6 and E7 oncoproteins cooperate to subvert critical host cell cycle
checkpoint control mechanisms in order to promote viral genome replication. This results not …

Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for
which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 …

For unknown reasons, there is huge variability in risk conferred by different HPV types and,
remarkably, strong differences even between closely related variant lineages within each …

Integration of human papillomavirus (HPV) DNA into the host genome can be a driver
mutation in cervical carcinoma. Identification of HPV integration at base resolution has been …