A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques
C Ziegert, N Wentzensen, S Vinokurova, F Kisseljov… - Oncogene, 2003 - nature.com
Persistent infections with high-risk human papillomaviruses (HPVs) induce dysplastic
lesions of the lower genital tract. Some of these lesions eventually progress to invasive …
lesions of the lower genital tract. Some of these lesions eventually progress to invasive …
[HTML][HTML] Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV-tumors
Background Human papillomavirus positive (HPV+) head and neck squamous cell
carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and …
carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and …
[HTML][HTML] Multiplex identification of human papillomavirus 16 DNA integration sites in cervical carcinomas
B Xu, S Chotewutmontri, S Wolf, U Klos, M Schmitz… - PloS one, 2013 - journals.plos.org
Cervical cancer is caused by high-risk human papillomaviruses (HPV), in more than half of
the worldwide cases by HPV16. Viral DNA integration into the host genome is a frequent …
the worldwide cases by HPV16. Viral DNA integration into the host genome is a frequent …
[HTML][HTML] Epigenetic alterations in human papillomavirus-associated cancers
D Soto, C Song, ME McLaughlin-Drubin - Viruses, 2017 - mdpi.com
Approximately 15–20% of human cancers are caused by viruses, including human
papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins …
papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins …
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers
ML Gillison, K Akagi, W Xiao, B Jiang… - Genome …, 2019 - genome.cshlp.org
Human papillomavirus (HPV) is a necessary but insufficient cause of a subset of oral
squamous cell carcinomas (OSCCs) that is increasing markedly in frequency. To identify …
squamous cell carcinomas (OSCCs) that is increasing markedly in frequency. To identify …
[HTML][HTML] Genomic and transcriptomic characterization links cell lines with aggressive head and neck cancers
Cell lines are important tools for biological and preclinical investigation, and establishing
their relationship to genomic alterations in tumors could accelerate functional and …
their relationship to genomic alterations in tumors could accelerate functional and …
[HTML][HTML] Human papillomavirus genomics: Understanding carcinogenicity
CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes
Cervical cancer is the most common cancer affecting sub-Saharan African women and is
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …
[HTML][HTML] Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell …
Human papillomavirus (HPV) DNA is detected in up to 80% of oropharyngeal carcinomas
(OPC) and this HPV positive disease has reached epidemic proportions. To increase our …
(OPC) and this HPV positive disease has reached epidemic proportions. To increase our …
Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes
MR Pett, WOF Alazawi, I Roberts, S Dowen, DI Smith… - Cancer research, 2004 - AACR
Whereas two key steps in cervical carcinogenesis are integration of high-risk human
papillomavirus (HR-HPV) and acquisition of an unstable host genome, the temporal …
papillomavirus (HR-HPV) and acquisition of an unstable host genome, the temporal …