A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques

C Ziegert, N Wentzensen, S Vinokurova, F Kisseljov… - Oncogene, 2003 - nature.com
Persistent infections with high-risk human papillomaviruses (HPVs) induce dysplastic
lesions of the lower genital tract. Some of these lesions eventually progress to invasive …

[HTML][HTML] Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV-tumors

M Lechner, GM Frampton, T Fenton, A Feber… - Genome medicine, 2013 - Springer
Background Human papillomavirus positive (HPV+) head and neck squamous cell
carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and …

[HTML][HTML] Multiplex identification of human papillomavirus 16 DNA integration sites in cervical carcinomas

B Xu, S Chotewutmontri, S Wolf, U Klos, M Schmitz… - PloS one, 2013 - journals.plos.org
Cervical cancer is caused by high-risk human papillomaviruses (HPV), in more than half of
the worldwide cases by HPV16. Viral DNA integration into the host genome is a frequent …

[HTML][HTML] Epigenetic alterations in human papillomavirus-associated cancers

D Soto, C Song, ME McLaughlin-Drubin - Viruses, 2017 - mdpi.com
Approximately 15–20% of human cancers are caused by viruses, including human
papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins …

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers

ML Gillison, K Akagi, W Xiao, B Jiang… - Genome …, 2019 - genome.cshlp.org
Human papillomavirus (HPV) is a necessary but insufficient cause of a subset of oral
squamous cell carcinomas (OSCCs) that is increasing markedly in frequency. To identify …

[HTML][HTML] Genomic and transcriptomic characterization links cell lines with aggressive head and neck cancers

H Cheng, X Yang, H Si, AD Saleh, W Xiao, J Coupar… - Cell reports, 2018 - cell.com
Cell lines are important tools for biological and preclinical investigation, and establishing
their relationship to genomic alterations in tumors could accelerate functional and …

[HTML][HTML] Human papillomavirus genomics: Understanding carcinogenicity

CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …

Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes

A Gagliardi, VL Porter, Z Zong, R Bowlby, E Titmuss… - Nature …, 2020 - nature.com
Cervical cancer is the most common cancer affecting sub-Saharan African women and is
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …

[HTML][HTML] Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell …

TJ Nulton, AL Olex, M Dozmorov, IM Morgan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) DNA is detected in up to 80% of oropharyngeal carcinomas
(OPC) and this HPV positive disease has reached epidemic proportions. To increase our …

Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes

MR Pett, WOF Alazawi, I Roberts, S Dowen, DI Smith… - Cancer research, 2004 - AACR
Whereas two key steps in cervical carcinogenesis are integration of high-risk human
papillomavirus (HR-HPV) and acquisition of an unstable host genome, the temporal …