Of the~ 60 human papillomavirus (HPV) genotypes that infect the cervicovaginal epithelium,
only 12–13 “high-risk” types are well-established as causing cervical cancer, with HPV16 …

The development of invasive cervical cancer is associated with human papillomavirus (HPV)
infection and subsequent integration into the host epithelium. More than 99% of cervical …

High-risk human papillomaviruses (HPVs) activate the ataxia telangiectasia mutated-
dependent (ATM) DNA damage response as well as the ataxia telangiectasia mutated …

HPV DNA integration into the host genome is a characteristic but not an exclusive step
during cervical carcinogenesis. It is still a matter of debate whether viral integration …

Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …

Somatic genome rearrangements are thought to play important roles in cancer development.
We optimized a long-span paired-end-tag (PET) sequencing approach using 10-Kb …

Squamous cell carcinomas (SCCs) arising from aerodigestive or anogenital epithelium that
are associated with the human papillomavirus (HPV) are far more readily cured with …

We applied a newly developed bioinformatics system called VirusScan to investigate the
viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide. Recently, the incidence of oropharyngeal cancer (OPC) has increased markedly …

Background Human Papillomavirus type 16 (HPV16) causes over half of all cervical cancer
and some HPV16 variants are more oncogenic than others. The genetic basis for the …