Neuroprotective and Anti-Apoptotic Propensity of Bacopa monniera Extract Against Sodium Nitroprusside Induced Activation of iNOS, Heat Shock Proteins and …

MD Pandareesh, T Anand - Neurochemical research, 2014 - Springer
Sodium nitroprusside (SNP) is a widely used nitric oxide (NO) donor, known to exert nitrative
stress by up-regulation of inducible nitric oxide synthase (iNOS). Nω-nitro-l-arginine-methyl …

Bacopa monnieri Extract Offsets Rotenone-Induced Cytotoxicity in Dopaminergic Cells and Oxidative Impairments in Mice Brain

GK Shinomol, RB Mythri, MM Srinivas Bharath… - Cellular and molecular …, 2012 - Springer
Bacopa monnieri (BM), an ayurvedic medicinal herb is widely known for its memory
enhancing ability and improvement of brain function. In this study, we tested the hypothesis …

Anti-apoptotic mechanism of Bacoside rich extract against reactive nitrogen species induced activation of iNOS/Bax/caspase 3 mediated apoptosis in L132 cell line

T Anand, MD Pandareesh, PV Bhat, M Venkataramana - Cytotechnology, 2014 - Springer
Nitric oxide is a highly reactive free radical gas that reacts with a wide range of bio-
molecules to produce reactive nitrogen species and exerts nitrative stress. Bacopa monniera …

Neuromodulatory Propensity of Bacopa monnieri Leaf Extract Against 3-Nitropropionic Acid-Induced Oxidative Stress: In Vitro and In Vivo Evidences

GK Shinomol, MMS Bharath, Muralidhara - Neurotoxicity Research, 2012 - Springer
We previously reported the propensity of Bacopa monnieri (BM) leaf powder to modulate
endogenous levels of oxidative stress markers in the brain of prepubertal mice. In this study …

[HTML][HTML] Bacopa monnieri protects SH-SY5Y cells against tert-Butyl hydroperoxide-induced cell death via the ERK and PI3K pathways

K Petcharat, M Singh, K Ingkaninan, J Attarat… - Siriraj medical …, 2015 - ncbi.nlm.nih.gov
Objective Oxidative stress plays an important role in the pathological processes of various
neurodegenerative diseases. Bacopa monnieri (BM) has a potent antioxidant property …

Assessment of the mechanistic role of an Indian traditionally used ayurvedic herb Bacopa monnieri (L.) Wettst. for ameliorating oxidative stress in neuronal cells

S Ghosh, V Kumar, H Mukherjee, S Saini… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance This study has important ethnopharmacological
implications since it systematically investigated the therapeutic potential of Bacopa monnieri …

Role of ethanolic extract of Bacopa monnieri against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) induced mice model via inhibition of apoptotic pathways …

B Singh, S Pandey, SK Yadav, R Verma, SP Singh… - Brain research …, 2017 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease which causes rigidity, resting
tremor and postural instability. The neuroprotective effects of an ethanolic extract of Bacopa …

Neuroprotective, Neurotrophic and Anti-oxidative Role of Bacopa monnieri on CUS Induced Model of Depression in Rat

S Kumar, AC Mondal - Neurochemical research, 2016 - Springer
Major depression is a life threatening neuropsychiatric disorder that produces mental illness
and major cause of morbidity. The present study was conducted to evaluate the …

Neuroprotective effect of Bacopa monniera on ischemia induced brain injury

MK Saraf, S Prabhakar, A Anand - Pharmacology Biochemistry and …, 2010 - Elsevier
PURPOSE: Brain stroke is a leading cause of death without effective treatment. B. monniera,
an Indian herbal medicine, exerts antioxidant activity and antistress activity by modulating …

[HTML][HTML] α-Bisabolol, a dietary bioactive phytochemical attenuates dopaminergic neurodegeneration through modulation of oxidative stress, neuroinflammation and …

H Javed, MFN Meeran, S Azimullah, L Bader Eddin… - Biomolecules, 2020 - mdpi.com
Rotenone (ROT), a plant-derived pesticide is a well-known environmental neurotoxin
associated with causation of Parkinson's disease (PD). ROT impairs mitochondrial …