Many different approaches have been developed to improve the efficiency of animal cloning
by somatic cell nuclear transfer (SCNT), one of which is to modify histone acetylation levels …

Until now, the efficiency of animal cloning by somatic cell nuclear transfer (SCNT) has
remained low. Efforts to improve cloning efficiency have demonstrated a positive role of …

The efficiency of somatic cell nuclear transfer (SCNT) is low in the rabbit. So far, there have
been few live births reported and most clones died within the first 3 weeks after birth. It has …

The low success rate of somatic cell nuclear transfer (SCNT) is primarily due to incomplete
reprogramming of the transferred nuclei. As an inhibitor of histone deacetylase, trichostatin A …

We previously demonstrated that the histone deacetylase inhibitor, trichostatin A (TSA),
improves the development of cat-cow interspecies somatic cell nuclear transfer (iSCNT) …

Although cloning by somatic cell nuclear transfer (SCNT) has been achieved in various
mammalian species, its efficiency has been very low (Han et al. 2003 Theriogenology 59, 33 …

Epigenetic modification influences reprogramming and subsequent development of somatic
cell nuclear transfer (SCNT) embryos. Such modification includes an increase in histone …

We studied the effects of trichostatin A (TSA), a histone deacetylase inhibitor, on the
development of bovine somatic cell nuclear transfer (SCNT) embryos by investigating (1) the …

Abnormal epigenetic modification is supposed to be one of factors accounting for inefficient
reprogramming of the donor cell nuclei in ooplasm after somatic cell nuclear transfer …

Successful cloning by somatic cell nuclear transfer (SCNT) requires a reprogramming
process in which the epigenetic state of a differentiated donor nucleus must be converted …