The endocannabinoid system is a complex system with endogenous ligands, synthesis and
transport processes, specific receptors (CB1 and CB2) and intracellular degrading enzymes …

The endocannabinoid system elicits multiple physiologic functions that are not fully
understood. Antagonism of cannabinoid type 1 (CB1) receptors has been the only …

Over the past 15 years, research on the endogenous cannabinoid (CB) system—now
usually referred to as the endocannabinoid system (ECS)—has identified the significant …

There is considerable evidence that the endocannabinoid (endogenous cannabinoid)
system plays a significant role in appetitive drive and associated behaviours. It is therefore …

It has long been known that marihuana consumption acutely increases appetite (Hollister,
1971) and decreases body temperature (Borgen et al., 1973). These effects predicted that …

The endogenous cannabinoid system is a novel, remarkably elaborate physiological
signaling system, comprising the recently identified endogenous cannabinoid ligands, their …

Obesity rates are increasing worldwide and there is a need for novel therapeutic treatment
options. The endocannabinoid system has been linked to homeostatic processes, including …

Endocannabinoids acting via CB 1 receptors (CB 1 R) play a critical role in regulating
energy homeostasis, which was the rationale for the pharmaceutical development of CB 1 R …

The impact of visceral obesity epidemic on the incidence of diabetes mellitus and
cardiovascular disease is a major concern in the public health management. Even if lifestyle …

Recent studies have provided evidence that the endocannabinoid (EC) system has very
significant effects on energy balance and metabolism through the central control of appetite …