Background/Aims: Liver fibrosis is one of the most important and characteristic histologic
alterations in progressive and chronic liver diseases. Thus, in both clinical and experimental …

Background/Aims: Liver fibrosis is mainly evaluated by qualitative histological examination.
Although histological semi-quantitative scores and quantitative determination with image …

Introduction: Semiquantitative evaluation of liver specimens is considered the standard
method for measuring fibrosis; however, these systems lack the precision of a quantitative …

Background/Aim: Digital image analysis (DIA) allows quantitative assessment of fibrosis on
liver biopsy. Accurate determination of a threshold greyscale level representing fibrous …

Hepatic fibrogenesis may gradually result to cirrhosis due to the accumulation of
extracellular matrix components as a response to liver injury. Thus, therapeutic decisions in …

The evaluation of hepatic fibrosis on histological sections is of great interest for the staging
and follow–up of chronic liver disease. Because no reliable scoring system is yet available …

Liver fibrosis is currently described quite subjectively or, at best, semiquantitatively by
scoring systems. In order to measure the severity of liver fibrosis quantitatively and to …

Background Computer-based morphometry can minimize subjectivity in the assessment of
liver fibrosis. An image processing program was developed with Delphi for the quantification …

Background: The precise quantification of fibrous tissue in liver biopsy sections is extremely
important in the classification, diagnosis and grading of chronic liver disease, as well as in …

There is now adequate evidence to indicate that liver fibrosis is a dynamic rather than a
static process and as effective antiviral and other specific therapies became available …