Objective: This study was conducted to assess the thromboxane (TX) dependence of
biochemical and functional indexes used to monitor the effect of low-dose aspirin …

Background—Thrombotic events still occur in aspirin-treated patients with coronary artery
disease. Methods and Results—To better understand aspirin “resistance,” serum …

Objectives: Although the concept of aspirin resistance is extensively reported in medical
literature, its precise mechanisms and clinical outcomes are largely unknown. In this study …

Dear Sir, The concept of aspirin resistance was born together with the observation that
aspirin can interfere with factors of the hemostatic system [1]. Indeed as early as 1966, Quick …

Resistance to inhibition of platelet function by aspirin may contribute to future myocardial
infarction and stroke. Adverse cardiovascular outcomes have been associated with aspirin …

Background—The antiplatelet effect of aspirin is attributed to platelet cyclooxygenase-1
inhibition. Controversy exists on the prevalence of platelet resistance to aspirin in patients …

We determined the prevalence and clinical predictors of aspirin resistance by prospectively
studying 325 patients with stable cardiovascular disease who were receiving aspirin (325 …

Salicylates have been used to treat pain and inflammation associated with rheumatism and
other conditions since ancient times. The Assyrians initially described the use of willow …

Background: Aspirin 'resistance'is a widely used term for hyporesponsiveness to aspirin in a
platelet function test. Serum thromboxane (TX) B 2 is the most specific test of aspirin's effect …

Objectives: We investigated the occurrence of pharmacodynamic interaction between low-
dose aspirin and naproxen. Background: The uncertainty of cardioprotection by naproxen …