[HTML][HTML] Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study

M Vithayathil, P Carter, S Kar, AM Mason… - PLoS …, 2021 - journals.plos.org
Background Evidence for the impact of body size and composition on cancer risk is limited.
This mendelian randomisation (MR) study investigates evidence supporting causal …

High body mass index and cancer risk—a Mendelian randomisation study

M Benn, A Tybjærg-Hansen, GD Smith… - European journal of …, 2016 - Springer
High body mass index (BMI) has been associated with increased risk of some cancer.
Whether these reflect causal associations is unknown. We examined this issue. Using a …

[HTML][HTML] Obesity, fat distribution and risk of cancer in women and men: a Mendelian randomisation study

NY Loh, W Wang, R Noordam, C Christodoulides - Nutrients, 2022 - mdpi.com
Obesity and upper-body fat distribution are independent, cardiometabolic risk factors but
whether they also display comparable associations with cancer risk is unknown. We …

[HTML][HTML] Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5· 24 million UK adults

K Bhaskaran, I Douglas, H Forbes, I dos-Santos-Silva… - The lancet, 2014 - thelancet.com
Background High body-mass index (BMI) predisposes to several site-specific cancers, but a
large-scale systematic and detailed characterisation of patterns of risk across all common …

[HTML][HTML] Height and overall cancer risk and mortality: evidence from a Mendelian randomisation study on 310,000 UK Biobank participants

JS Ong, J An, MH Law, DC Whiteman, RE Neale… - British journal of …, 2018 - nature.com
Background Observational studies have shown that being taller is associated with greater
cancer risk. However, the interpretation of such studies can be hampered by important …

[HTML][HTML] Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study

AM Sedlmeier, V Viallon, P Ferrari… - British Journal of …, 2023 - nature.com
Background Classical anthropometric traits may fail to fully represent the relationship of
weight, adiposity, and height with cancer risk. We investigated the associations of body …

[HTML][HTML] A prospective investigation of body size, body fat composition and colorectal cancer risk in the UK Biobank

LS Ortega, KE Bradbury, AJ Cross, JS Morris… - Scientific reports, 2017 - nature.com
Obesity has been consistently associated with a greater colorectal cancer risk, but this
relationship is weaker among women. In the UK Biobank, we investigated the associations …

Assessment of causal effects of visceral adipose tissue on risk of cancers: a Mendelian randomization study

Y Lu, H Tang, P Huang, J Wang, P Deng… - International journal …, 2022 - academic.oup.com
Background Despite the established association between obesity and cancer risk, it remains
unclear whether visceral obesity is causally related to cancer risk and whether it is more pro …

Mendelian randomization study of body mass index and colorectal cancer risk

AP Thrift, J Gong, U Peters, J Chang-Claude… - … Biomarkers & Prevention, 2015 - AACR
Background: High body mass index (BMI) is consistently linked to increased risk of
colorectal cancer for men, whereas the association is less clear for women. As risk estimates …

[HTML][HTML] Association of body-shape phenotypes with imaging measures of body composition in the UK Biobank cohort: relevance to colon cancer risk

S Christakoudi, KK Tsilidis, E Evangelou, E Riboli - BMC cancer, 2021 - Springer
Background Body mass index (BMI), waist and hip circumference are strongly correlated
and do not reflect body composition. A Body Shape Index (ABSI) and Hip Index (HI) define …