Mammalian experiments provide clear evidence of male line transgenerational effects on
health and development from paternal or ancestral early-life exposures such as diet or …

Transgenerational effects of maternal nutrition or other environmental 'exposures' are well
recognised, but the possibility of exposure in the male influencing development and health …

Epidemiological studies have shown that the environment experienced in early life can
'programme'susceptibility to later disease. Furthermore, there is increasing evidence that …

What are the effects of our environment on human development and the next generation?
Numerous studies have provided ample evidence that a healthy environment and lifestyle of …

Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …

The possibility that parental life experiences and environmental exposures influence mental
and physical health across generations is an important concept in biology and medicine …

Since Mendel, studies of phenotypic variation and disease risk have emphasized
associations between genotype and phenotype among affected individuals in families and …

BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …

Traditionally, we understand that individual phenotypes result primarily from inherited
genetic variants together with environmental exposures. However, many studies showed …

Though there are multiple routes through which parents can influence their offspring, recent
studies of environmentally induced epigenetic variation have highlighted the role of non …