It has been shown that patients with chronic obstructive pulmonary disease (COPD) develop
dynamic hyperinflation (DH), which contributes to dyspnoea and exercise intolerance …

Expiratory flow limitation (EFL), which promotes dynamic hyperinflation and increased work
of breathing, often occurs in chronic obstructive pulmonary disease (COPD). The purpose of …

Background: Inhaled bronchodilators can increase exercise capacity in chronic obstructive
pulmonary disease (COPD) by reducing dynamic hyperinflation, but treatment is not always …

Dynamic hyperinflation (DH) is a major pathophysiologic consequence of airflow limitation
during exercise in patients with chronic obstructive pulmonary disease (COPD) and an …

This study examined the effects of bronchodilator-induced reductions in lung hyperinflation
on breathing pattern, ventilation and dyspnoea during exercise in chronic obstructive …

Expiratory airway collapse is a characteristic feature in patients with chronic obstructive
pulmonary disease (COPD). We hypothesized that this collapse might mask the effects of …

Formoterol fumarate is a β2-agonist bronchodilator that combines a fast onset of action with
a long duration of action. Its fast onset of action is well documented in asthma but has not …

Background: Some patients with irreversible chronic obstructive pulmonary disease (COPD)
experience subjective benefit from long acting bronchodilators without change in forced …

Background: Although airflow limitation improved by inhaled anticholinergic drugs varies
among individuals with chronic obstructive pulmonary disease (COPD), the relationship …

We examined whether a pretreatment with formoterol, oxitropium bromide, or salmeterol
might modify the dose-response curves to inhaled salbutamol in patients with stable and …