An efficient and convenient method enabling direct amination of unactivated methylene C
(sp3)–H bonds to form C–N bonds with azodiformates as amino source is described. This …

A palladium-catalyzed intramolecular amination of alkenes with retention of olefin
functionalization was achieved under mild reaction conditions. In the presence of palladium …

Palladium-catalyzed intermolecular amination of unactivated C (sp3)–H bonds was
developed. Using NFSI as both the amino source and the oxidant, this protocol operates …

PdII‐catalyzed intermolecular amination of unactivated C (sp3) H bonds has been
successfully developed for the first time. This method provides a new way to achieve the …

A palladium catalyzed intramolecular C (sp2)–H amination using a readily available
aluminum nitrate (Al (NO3) 3· 9H2O) as the oxidant is reported. The C–H amination is …

Efficient methods have been developed to synthesize azetidine, pyrrolidine, and indoline
compounds via palladium-catalyzed intramolecular amination of C–H bonds at the γ and δ …

Nitrogen-containing compounds are the most common structural architectures in drug
candidates, natural and biological products, and small-molecule therapeutics. Within the …

The cross-coupling of C–N bond directly from inert C–H bonds is an ideal approach to
synthesize saturated azacycles due to its high efficiency and atom economy. In this article, a …

Pd-Catalyzed intramolecular allylic C–H amination of 1, 1-disubstituted alkenyl amines with
various allylic tethers (X= O, NMs, CH2) was developed. This process allows for the …

The carbonylative coupling of aryl halides with unactivated alkenes remains a challenge,
because of the low reactivity of acyl-palladium intermediate to the olefins. In this paper, a …