Prominent clinical models of chronic pain propose a fundamental role of classical
conditioning in the development of pain-related disability. If classical conditioning is key to …

Human fear conditioning research since Watson's case study on “Little Albert” has vastly
evolved and its impact today is reaching far beyond phobic anxiety. This review focuses on …

Background Classical conditioning has frequently been shown to be capable of evoking fear
of pain and avoidance behavior in the context of chronic pain. However, whether pain itself …

Background. Clinical scenarios of repeated pain usually involve both nociceptive and non-
nociceptive input. It is likely that associations between these stimuli are learned over time …

A systematic literature review and meta-analysis were undertaken to determine if
conditioned pain modulation is dysfunctional in populations with chronic pain. Studies that …

The fear-avoidance model advances fear of pain as a key factor in the origins of chronic pain
disability. Initial evidence in those with chronic back pain reveals that exposure therapy …

The primary aim of the current study was to experimentally test whether pain-related fear can
be acquired through observational learning, whether extinction occurs after actual exposure …

Abstract Purpose of Review It has been known for decades that classical conditioning
influences pain perception. However, the precise relationship between conditioning and …

A novel pain-relevant fear conditioning paradigm that demonstrates the involvement of
associative learning in the acquisition of fear of movement-related pain. ABSTRACT Current …

Recent evidence indicates that pain-related fear can be acquired through associative
learning. In the clinic, however, spreading of fear and avoidance is observed beyond …