Perineuronal nets and their role in synaptic homeostasis

M Bosiacki, M Gąssowska-Dobrowolska… - International journal of …, 2019 - mdpi.com
Extracellular matrix (ECM) molecules that are released by neurons and glial cells form
perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose …

Looking inside the matrix: perineuronal nets in plasticity, maladaptive plasticity and neurological disorders

C De Luca, M Papa - Neurochemical Research, 2016 - Springer
The integrity of the central nervous system (CNS) matrix is crucial for its proper function.
Loss of the lattice-like structure compromise synaptic stability and can lead to the disruption …

[HTML][HTML] Perineuronal nets and CNS plasticity and repair

D Carulli, JCF Kwok, T Pizzorusso - Neural Plasticity, 2016 - ncbi.nlm.nih.gov
The extracellular matrix (ECM) of the nervous system regulates numerous events during
development, from neurogenesis and gliogenesis to circuitry formation, as well as in …

Protective properties of neural extracellular matrix

A Suttkus, M Morawski, T Arendt - Molecular neurobiology, 2016 - Springer
The extracellular matrix (ECM) of the central nervous system (CNS) occupies a large part of
the neural tissue. It serves a variety of functions ranging from support of cell migration and …

[HTML][HTML] A glial perspective on the extracellular matrix and perineuronal net remodeling in the central nervous system

BP Tewari, L Chaunsali, CE Prim… - Frontiers in cellular …, 2022 - frontiersin.org
A structural scaffold embedding brain cells and vasculature is known as extracellular matrix
(ECM). The physical appearance of ECM in the central nervous system (CNS) ranges from a …

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

JW Fawcett, T Oohashi, T Pizzorusso - Nature Reviews Neuroscience, 2019 - nature.com
Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

The perineuronal net component of the extracellular matrix in plasticity and epilepsy

PA McRae, BE Porter - Neurochemistry international, 2012 - Elsevier
During development the extracellular matrix (ECM) of the central nervous system (CNS)
facilitates proliferation, migration, and synaptogenesis. In the mature nervous system due to …

[HTML][HTML] Extracellular matrix in neural plasticity and regeneration

YA Chelyshev, IM Kabdesh… - Cellular and molecular …, 2022 - Springer
The extracellular matrix (ECM) is a fundamental component of biological tissues. The ECM
in the central nervous system (CNS) is unique in both composition and function. Functions …

Neuron‐glia interactions in neural plasticity: contributions of neural extracellular matrix and perineuronal nets

E Dzyubenko, C Gottschling, A Faissner - Neural plasticity, 2016 - Wiley Online Library
Synapses are specialized structures that mediate rapid and efficient signal transmission
between neurons and are surrounded by glial cells. Astrocytes develop an intimate …

Casting a wide net: role of perineuronal nets in neural plasticity

BA Sorg, S Berretta, JM Blacktop… - Journal of …, 2016 - Soc Neuroscience
Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity in the adult CNS. They appear …