[HTML][HTML] Structural variation of chondroitin sulfate chains contributes to the molecular heterogeneity of perineuronal nets

S Miyata, S Nadanaka, M Igarashi… - Frontiers in Integrative …, 2018 - frontiersin.org
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix
structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath …

The crosstalk of hyaluronan-based extracellular matrix and synapses

R Frischknecht, CI Seidenbecher - Neuron glia biology, 2008 - cambridge.org
Many neurons and their synapses are enwrapped in a brain-specific form of the extracellular
matrix (ECM), the so-called perineuronal net (PNN). It forms late in the postnatal …

Crosstalk between glia, extracellular matrix and neurons

I Song, A Dityatev - Brain research bulletin, 2018 - Elsevier
Extracellular matrix (ECM) molecules in the central nervous system form highly organized
ECM structures around cell somata, axon initial segments, and synapses and play …

Proteolytic remodeling of perineuronal nets: effects on synaptic plasticity and neuronal population dynamics

P Lorenzo Bozzelli, S Alaiyed, E Kim, S Villapol… - Neural …, 2018 - Wiley Online Library
The perineuronal net (PNN) represents a lattice‐like structure that is prominently expressed
along the soma and proximal dendrites of parvalbumin‐(PV‐) positive interneurons in varied …

Matrix metalloproteinases, neural extracellular matrix, and central nervous system pathology

C De Luca, M Papa - Progress in molecular biology and translational …, 2017 - Elsevier
The functionality and stability of the central nervous system (CNS) pabulum, called neural
extracellular matrix (nECM), is paramount for the maintenance of a healthy network. The …

The extracellular environment of the CNS: influence on plasticity, sprouting, and axonal regeneration after spinal cord injury

S Quraishe, LH Forbes, MR Andrews - Neural plasticity, 2018 - Wiley Online Library
The extracellular environment of the central nervous system (CNS) becomes highly
structured and organized as the nervous system matures. The extracellular space of the …

Perineuronal net formation and structure in aggrecan knockout mice

KA Giamanco, M Morawski, RT Matthews - Neuroscience, 2010 - Elsevier
Perineuronal nets (PNNs) are specialized substructures of the neural extracellular matrix
(ECM) which envelop the cell soma and proximal neurites of particular sets of neurons with …

Neurocan contributes to perineuronal net development

S Schmidt, T Arendt, M Morawski, M Sonntag - Neuroscience, 2020 - Elsevier
Perineuronal nets (PNs) are matrix molecule assemblies surrounding neuronal somata,
dendrites and axon initial segments in a lattice-like appearance. PN molecules are involved …

[HTML][HTML] The extracellular matrix and perineuronal nets in memory

JW Fawcett, M Fyhn, P Jendelova, JCF Kwok… - Molecular …, 2022 - nature.com
All components of the CNS are surrounded by a diffuse extracellular matrix (ECM)
containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans …

Formation and remodeling of the brain extracellular matrix in neural plasticity: Roles of chondroitin sulfate and hyaluronan

S Miyata, H Kitagawa - Biochimica et Biophysica Acta (BBA)-General …, 2017 - Elsevier
Background The extracellular matrix (ECM) of the brain is rich in glycosaminoglycans such
as chondroitin sulfate (CS) and hyaluronan. These glycosaminoglycans are organized into …