Neuroendocrine and neuroimmune markers in PTSD: pre-, peri-and post-trauma glucocorticoid and inflammatory dysregulation

M Olff, M van Zuiden - Current Opinion in Psychology, 2017 - Elsevier
Highlights•Low cortisol, enhanced GR function and a pro-inflammatory state have been
repeatedly observed in subpopulations of PTSD patients.•Biological dysregulation may …

[PDF][PDF] Endocrine aspects of PTSD: Hypothalamic-pituitary-adrenal (HPA) axis and beyond

NP Daskalakis, MA McGill, A Lehrner… - … guide to post-traumatic …, 2016 - researchgate.net
Post-traumatic stress disorder is a severe, debilitating mental disorder with multiple
symptoms that span biological systems and present with medical comorbidities. This …

Posttraumatic stress disorder under ongoing threat: a review of neurobiological and neuroendocrine findings

I Fragkaki, K Thomaes, M Sijbrandij - European journal of …, 2016 - Taylor & Francis
Background Although numerous studies have investigated the neurobiology and
neuroendocrinology of posttraumatic stress disorder (PTSD) after single finished trauma …

Advances in understanding neuroendocrine alterations in PTSD and their therapeutic implications

R Yehuda - Annals of the new York Academy of Sciences, 2006 - Wiley Online Library
The findings from investigations of the neuroendocrinology of posttraumatic stress disorder
(PTSD) have highlighted alterations that have not historically been associated with …

RETRACTED: Linking plasma cortisol levels to phenotypic heterogeneity of posttraumatic stress symptomatology

CAC Horn, RH Pietrzak, S Corsi-Travali, A Neumeister - 2014 - Elsevier
The article mentioned above has been retracted by R. Dantzer, Editor-in-Chief, in response
to a request from the Office of Research Integrity, Department of Health and Human …

Repeated assessments of endocrine-and immune-related changes in posttraumatic stress disorder

A Vidović, K Gotovac, M Vilibić, A Sabioncello… - …, 2011 - karger.com
Objective: It is assumed that stress-related changes in the endocrine and immune systems
are key mediators involved in the development of diseases associated with posttraumatic …

Neuroendocrine aspects of PTSD

R Yehuda - Anxiety and anxiolytic drugs, 2005 - Springer
This chapter discussed how neuroendocrine findings in posttraumatic stress disorder
(PTSD) potentially inform hypothalamic-pituitary-adrenal (HPA) alterations in PTSD and …

A short review on the psychoneuroimmunology of posttraumatic stress disorder: from risk factors to medical comorbidities

TWW Pace, CM Heim - Brain, behavior, and immunity, 2011 - Elsevier
Posttraumatic stress disorder (PTSD) is a serious and debilitating condition with a
prevalence rate of approximately 8% in the United States. Given the number of veterans …

Cortisol and the hypothalamic–pituitary–adrenal axis in PTSD

A Lehrner, N Daskalakis… - Posttraumatic Stress …, 2016 - Wiley Online Library
The acute stress response includes activation of the hypothalamic‐pituitary‐adrenal (HPA)
axis, which leads to the release of cortisol, a glucocorticoid. Through negative feedback …

Glucocorticoid-related predictors and correlates of post-traumatic stress disorder treatment response in combat veterans

R Yehuda, LC Pratchett, MW Elmes… - Interface …, 2014 - royalsocietypublishing.org
The identification of biomarkers for post-traumatic stress disorder (PTSD) and
resilience/recovery is critical for advancing knowledge about pathophysiology and treatment …