Optical fiber probe for biomedical Raman spectroscopy

JT Motz, M Hunter, LH Galindo, JA Gardecki… - Applied …, 2004 - opg.optica.org
In vitro experiments have demonstrated the ability of Raman spectroscopy to diagnose a
wide variety of diseases. Recent in vivo investigations performed with optical fiber probes …

Real-time Raman system for in vivo disease diagnosis

JT Motz, SJ Gandhi, OR Scepanovic… - … of biomedical optics, 2005 - spiedigitallibrary.org
Raman spectroscopy has been well established as a powerful in vitro method for studying
biological tissue and diagnosing disease. The recent development of efficient, high …

Study of fiber-optic probes for in vivo medical Raman spectroscopy

MG Shim, BC Wilson, E Marple, M Wach - Applied Spectroscopy, 1999 - opg.optica.org
Recent reports indicate that useful diagnostic information can be obtained from ex vivo
tissue by using near-infrared Raman spectroscopy. A fiber-optic-based Raman system has …

In-vivo Raman spectroscopy: from basics to applications

E Cordero, I Latka, C Matthäus… - Journal of biomedical …, 2018 - spiedigitallibrary.org
For more than two decades, Raman spectroscopy has found widespread use in biological
and medical applications. The instrumentation and the statistical evaluation procedures …

Developing fibre optic Raman probes for applications in clinical spectroscopy

O Stevens, IEI Petterson, JCC Day… - Chemical Society Reviews, 2016 - pubs.rsc.org
Raman spectroscopy has been shown by various groups over the last two decades to have
significant capability in discriminating disease states in bodily fluids, cells and tissues …

Tissue characterization using high wave number Raman spectroscopy

S Koljenovic, TC Bakker Schut… - … of biomedical optics, 2005 - spiedigitallibrary.org
Raman spectroscopy is a powerful diagnostic tool, enabling tissue identification and
classification. Mostly, the so-called fingerprint (∼ 400–1800 cm− 1) spectral region is used …

Fiber-optic probes for in vivo Raman spectroscopy in the high-wavenumber region

LF Santos, R Wolthuis, S Koljenović… - Analytical …, 2005 - ACS Publications
In vivo Raman spectroscopy, using fiber-optic probes is hindered by the intense background
signal, which is generated in the fused-silica fibers, in the fingerprint region of the Raman …

A subcutaneous Raman needle probe

JCC Day, N Stone - Applied spectroscopy, 2013 - journals.sagepub.com
Raman spectroscopy is a powerful tool for studying the biochemical composition of tissues
and cells in the human body. We describe the initial results of a feasibility study to design …

Real‐time in vivo cancer diagnosis using raman spectroscopy

W Wang, J Zhao, M Short, H Zeng - Journal of biophotonics, 2015 - Wiley Online Library
Raman spectroscopy has becoming a practical tool for rapid in vivo tissue diagnosis. This
paper provides an overview on the latest development of real‐time in vivo Raman systems …

Advances in real‐time fiber‐optic Raman spectroscopy for early cancer diagnosis: Pushing the frontier into clinical endoscopic applications

HPS Heng, C Shu, W Zheng, K Lin… - Translational …, 2021 - Wiley Online Library
Real‐time fiber‐optic Raman spectroscopy has emerged as a compelling approach for
biomedical diagnosis and characterization. This article reviews the following topics related …