Objective: To determine between timing and LT4 dose which was the more important factor
for IQ at 7 years in screened congenital hypothyroidism (CH). Methods: 131 children with CH …

Context The optimal levothyroxine (LT4) dose to treat congenital hypothyroidism (CH)
remains unclear, with debate over whether higher starting doses (> 10 µg/kg) are necessary …

To evaluate the effect of different initial levothyroxine (LT4) replacement doses on growth
and intellectual outcome in patients with congenital hypothyroidism (CH) detected by …

Purpose Delayed treatment of congenital hypothyroidism (CH) is a common cause of mental
retardation. The aim of the present study was to evaluate intellectual outcomes in preschool …

The influence of the initial LT 4 dose and some other factors on the intellectual development
was evaluated at 7 years of age in 47 congenitally hypothyroid children detected by the …

Objectives We designed a multicentre open prospective randomized trial to evaluate the risk-
benefit profile of two different initial treatment schemes with levothyroxine (L-T4), 10-12.5 …

Background: Thyroid hormones are essential for growth and brain development in
childhood. Although congenital hypothyroidism (CH) is the most common reason for mental …

Objectives: To test whether early treatment with a high initial dose of levothyroxine can
prevent suboptimal mental development in all neonates with congenital hypothyroidism …

Neonatal thyroid screening programs were first im-plemented in the mid-to late 1970s to
detect congenital hypothyroidism (CH) as soon after birth as possible and begin therapy …

OBJECTIVES: To compare neurodevelopmental outcomes in severe and moderate
congenital hypothyroidism (CH) among 3 different initial L-thyroxine doses and to examine …