Menopausal hormone replacement therapy has been widely used to alleviate the symptoms
of menopause and to decrease the detrimental effects of ovarian hormone loss on bone …

Colon cancer incidence and mortality rates are lower in females compared with males, and
numerous epidemiological studies suggest that estrogen replacement therapy (ERT) …

Clinical evidence suggests that estradiol replacement therapy reduces colon cancer risk in
'post'menopausal women. In colon epithelial cells, the estrogen receptor β (ERβ) is the …

Epidemiological data suggest a protective effect for estrogen replacement therapy on colon
cancer. The estrogen receptor (ER) is required for the action of estrogen. The ER-β isoform …

Estrogen replacement therapy in postmenopausal women is associated with a reduction in
colorectal cancer risk, potentially via interactions between 17β-estradiol (E2) and the …

Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

Knowledge regarding the expression of the recently cloned estrogen receptor β (ERβ) in
colonic mucosa is limited. In this study, we demonstrated that five human colon cancer cell …

Epidemiological and experimental evidence suggests that estrogen replacement therapy
reduces the risk of colon cancer in postmenopausal women. Estrogen receptor beta (ERβ) is …

Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …

Postmenopausal women on estrogen replacement therapy (ERT) have a reduced risk of
developing colon cancer compared with postmenopausal women not on ERT, suggesting a …