Cost–effectiveness of afatinib and erlotinib as second-line treatments for advanced squamous cell carcinoma of the lung

J Zhu, W He, M Ye, J Fu, YB Chu, YY Zhao… - Future …, 2018 - Future Medicine
Aim: To investigate the cost–effectiveness of afatinib and erlotinib as second-line therapy for
advanced squamous cell carcinoma of the lung. Materials & methods: A decision-analytic …

Evaluating the cost-effectiveness of afatinib after platinum-based therapy for the treatment of squamous non-small-cell lung cancer in France

M Pignata, C Chouaid, K Le Lay, L Luciani… - ClinicoEconomics …, 2017 - Taylor & Francis
Background and aims Lung cancer has the highest mortality rate of all cancers worldwide.
Non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancers and has an …

Cost-Effectiveness of Afatinib Versus Erlotinib for The Treatment of Squamous Non-Small Cell Lung Cancer in France After A First-Line Platinium Based Therapy

M Pignata, K Le Lay, L Luciani… - Value in …, 2017 - valueinhealthjournal.com
Objectives To assess the cost-effectiveness of afatinib compared to erlotinib for the treatment
of squamous NSCLC after first-line platinum based therapy from the French healthcare …

Cost-effectiveness analysis of EGFR mutation testing and afatinib versus gemcitabine-cisplatin as first-line therapy for advanced non-small-cell lung cancer in China

R You, J Liu, DBC Wu, XY Qian, B Lyu… - Cancer management …, 2019 - Taylor & Francis
Objective The purpose of this study was to evaluate the cost-effectiveness of the combined
use of afatinib and epidermal growth factor receptor (EGFR) testing versus gemcitabine …

Cost effectiveness analysis of afatinib versus pemetrexed-cisplatin for first-line treatment of locally advanced or metastatic EGFR mutation positive non-small-cell lung …

PT Tan, MIA Aziz, F Pearce, WT Lim, DBC Wu, K Ng - BMC cancer, 2018 - Springer
Background Non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancers and
is associated with a poor prognosis. Afatinib is an irreversible ErbB family blocker …

Afatinib vs erlotinib for second-line treatment of Chinese patients with advanced squamous cell carcinoma of the lung

S Lu, W Li, C Zhou, CP Hu, S Qin, G Cheng… - OncoTargets and …, 2018 - Taylor & Francis
Background The global Phase III LUX-Lung 8 trial (ClinicalTrials. gov: NCT1523587)
identified significant improvements in progression-free survival (PFS), overall survival (OS) …

Costs of adverse events associated with erlotinib or afatinib in first-line treatment of advanced EGFR-positive non-small cell lung cancer

D Isla, J De Castro, O Juan, S Grau… - ClinicoEconomics …, 2016 - Taylor & Francis
Objectives Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR-TKIs) are an
established treatment for advanced non-small cell lung cancer (NSCLC) with EGFR …

Cost-effectiveness of afatinib, gefitinib, erlotinib and pemetrexed-based chemotherapy as first-line treatments for advanced non-small cell lung cancer in China

X Gu, Q Zhang, YB Chu, YY Zhao, YJ Zhang, D Kuo… - Lung Cancer, 2019 - Elsevier
Purpose Tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) are
becoming the standard treatments for Chinese patients with advanced non-small cell lung …

Cost-effectiveness analysis of afatinib, erlotinib, and gefitinib as first-line treatments for EGFR mutation-positive non-small-cell lung cancer in Ontario, Canada

YJ Kim, M Oremus, HH Chen, T McFarlane… - …, 2021 - Springer
Objective The objective of this study was to compare the cost effectiveness of first-line
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for the treatment of …

EGFR mutation-guided use of afatinib, erlotinib and gefitinib for advanced non-small-cell lung cancer in Hong Kong–A cost-effectiveness analysis

JHS You, WCS Cho, W Ming, Y Li, C Kwan, K Au… - PLoS …, 2021 - journals.plos.org
Introduction Tyrosine kinase inhibitors (TKIs) therapy targets at epidermal growth factor
receptor (EGFR) gene mutations in non-small-cell lung cancer (NSCLC). We aimed to …