[HTML][HTML] Differentiated adaptive evolution, episodic relaxation of selective constraints, and pseudogenization of umami and sweet taste genes TAS1Rs in catarrhine …

G Liu, L Walter, S Tang, X Tan, F Shi, H Pan, C Roos… - Frontiers in …, 2014 - Springer
Background Umami and sweet tastes are two important basic taste perceptions that allow
animals to recognize diets with nutritious carbohydrates and proteins, respectively. Until …

Complex evolutionary history of the vertebrate sweet/umami taste receptor genes

P Feng, HB Zhao - Chinese Science Bulletin, 2013 - Springer
Adaptive evolution plays a role in the functional divergence and specialization of taste
receptors and the sense of taste is thought to be closely related to feeding ecology. To …

Relationships between bitter taste receptor gene evolution, diet, and gene repertoire in primates

P Feng, H Wang, X Liang, X Dong… - Genome Biology and …, 2024 - academic.oup.com
Bitter taste perception plays a critical role in deterring animals from consuming harmful and
toxic substances. To characterize the evolution of primate Tas2r, test the generality of Tas2r …

[HTML][HTML] Dietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals

Z Liu, G Liu, F Hailer, P Orozco-terWengel, X Tan… - Frontiers in …, 2016 - Springer
Background Bitter taste perception is essential for species with selective food intake,
enabling them to avoid unpalatable or toxic items. Previous studies noted a marked variation …

A new world monkey resembles human in bitter taste receptor evolution and function via a single parallel amino acid substitution

H Yang, S Yang, F Fan, Y Li, S Dai… - Molecular Biology …, 2021 - academic.oup.com
Bitter taste receptors serve as a vital component in the defense system against toxin intake
by animals, and the family of genes encoding these receptors has been demonstrated …

Frequent expansions of the bitter taste receptor gene repertoire during evolution of mammals in the Euarchontoglires clade

T Hayakawa, N Suzuki-Hashido… - Molecular Biology and …, 2014 - academic.oup.com
Genome studies of mammals in the superorder Euarchontoglires (a clade that comprises the
orders Primates, Dermoptera, Scandentia, Rodentia, and Lagomorpha) are important for …

[HTML][HTML] Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys

K Tsutsui, M Otoh, K Sakurai, N Suzuki-Hashido… - BMC evolutionary …, 2016 - Springer
Abstract Background New World monkeys (NWMs) are unique in that they exhibit
remarkable interspecific variation in color vision and feeding behavior, making them an …

[HTML][HTML] New insights on the evolution of the sweet taste receptor of primates adapted to harsh environments

NAM Tamrin, R Zainudin, Y Esa, H Alias, MNM Isa… - Animals, 2020 - mdpi.com
Simple Summary A sense of taste is vital to an animal's fitness. It enables animals to select
and ingest beneficial foods and avoid harmful substances in their daily lives. There have …

Lineage‐specific evolution of bitter taste receptor genes in the giant and red pandas implies dietary adaptation

L Shan, Q Wu, L Wang, L Zhang, F Wei - Integrative Zoology, 2018 - Wiley Online Library
Abstract Taste 2 receptors (TAS2R) mediate bitterness perception in mammals, thus are
called bitter taste receptors. It is believed that these genes evolved in response to species …

[HTML][HTML] Genetic variation in taste receptor pseudogenes provides evidence for a dynamic role in human evolution

D Risso, S Tofanelli, G Morini, D Luiselli… - BMC evolutionary …, 2014 - Springer
Background Human bitter taste receptors are encoded by a gene family consisting of 25
functional TAS2R loci. In addition, humans carry 11 TAS2R pseudogenes, some of which …