Proteasome‐mediated cleavage of the Y‐box‐binding protein 1 is linked to DNA‐damage stress response

AV Sorokin, AA Selyutina, MA Skabkin… - The EMBO …, 2005 - embopress.org
YB‐1 is a DNA/RNA‐binding nucleocytoplasmic shuttling protein whose regulatory effect on
many DNA‐and RNA‐dependent events is determined by its localization in the cell …

The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress

ER Kim, AA Selyutina, IA Buldakov, V Evdokimova… - Cell cycle, 2013 - Taylor & Francis
The Y-box binding protein 1 (YB-1) is a DNA/RNA-binding nucleocytoplasmic shuttling
protein whose regulatory effect on many DNA and RNA-dependent events is determined by …

Genotoxic stress-induced nuclear localization of oncoprotein YB-1 in the absence of proteolytic processing

SB Cohen, W Ma, VA Valova, M Algie, R Harfoot… - Oncogene, 2010 - nature.com
Abstract Y-box-binding protein 1 (YB-1) is an oncogenic transcription factor whose
overexpression and nuclear localization is associated with tumor progression and drug …

Inhibition of transcription induces phosphorylation of YB-1 at Ser102 and its accumulation in the nucleus

DA Kretov, DA Mordovkina, IA Eliseeva, DN Lyabin… - Cells, 2019 - mdpi.com
The Y-box binding protein 1 (YB-1) is an RNA/DNA-binding protein regulating gene
expression in the cytoplasm and the nucleus. Although mostly cytoplasmic, YB-1 …

Nuclear localization of Y-box factor YB1 requires wild-type p53

YF Zhang, C Homer, SJ Edwards, L Hananeia… - Oncogene, 2003 - nature.com
Nuclear localization and high levels of the Y-box binding protein YB1 appear to be important
indicators of drug resistance and tumor prognosis. YB1 also interacts with the p53 tumor …

The pleiotropic functions of the Y‐box‐binding protein, YB‐1

K Kohno, H Izumi, T Uchiumi, M Ashizuka… - …, 2003 - Wiley Online Library
The Y‐box‐binding protein (YB‐1) represents the most evolutionary conserved nucleic‐acid‐
binding protein currently known. YB‐1 is a member of the cold‐shock domain (CSD) protein …

YB‐1 protein: functions and regulation

DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …

Y box binding protein 1 (YB-1) oncoprotein at the hub of DNA proliferation, damage and cancer progression

F Sangermano, A Delicato, V Calabrò - Biochimie, 2020 - Elsevier
The Y Box binding protein 1 (YB-1) belongs to the highly conserved Cold Shock Domain
protein family and is a major component of messenger ribonucleoprotein particles (mRNPs) …

Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities

CRC van Roeyen, FG Scurt, S Brandt, VA Kuhl… - Cell Communication and …, 2013 - Springer
Background The Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene
transcription, mRNA processing, and translation. It remains elusive how YB-1 shuttling into …

Characterization of the 5′‐untranslated region of YB‐1 mRNA and autoregulation of translation by YB‐1 protein

T Fukuda, M Ashizuka, T Nakamura… - Nucleic acids …, 2004 - academic.oup.com
The eukaryotic Y‐box binding protein YB‐1 is involved in various biological processes,
including DNA repair, cell proliferation and the regulation of transcription and translation. YB …