This prospective epidemiological study was performed to establish the prevalence, risk
factors, and dynamics of pneumococcal colonization in community-dwelling (n= 109) and …

Benefits from influenza and 23-valent pneumococcal polysaccharide (23vPPV) vaccines
against invasive pneumococcal disease and laboratory confirmed influenza have been well …

Abstract Background: Infections due to Streptococcus pneumoniae are the major cause of
adult community-acquired pneumonia, especially in elderly persons with chronic medical …

Use of the pneumococcal conjugate vaccines among children in the US since 2000 has
dramatically reduced pneumococcal disease burden among adults. Significant vaccine …

Whether or not age by itself increases susceptibility to pneumococcal infections separate
from the effects of chronic disease is controversial. To address this issue, data collected for a …

Introduction Pneumococcus is a commensal of the upper respiratory tract and colonization is
common in young children. Carriage studies have provided insights on vaccine effects in …

Pneumococcal disease can be divided into invasive disease, ie when bacteria are detected
in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs …

There have been few surveys of Streptococcus pneumoniae and Neisseria meningitidis
carriage in sick or frail elderly people who, with the very young, comprise the group who are …

Streptococcus pneumoniae has been recognised as a major cause of pneumonia since the
time of Sir William Osler. Drug-resistant S. pneumoniae (DRSP), which have gradually …

Background Although a considerable amount is known about the effect of age on the
manifestations and outcomes of pneumonia, the same is not true for invasive pneumococcal …