[HTML][HTML] Effect of early versus deferred antiretroviral therapy for HIV on survival

MM Kitahata, SJ Gange, AG Abraham… - … England Journal of …, 2009 - Mass Medical Soc
Background The optimal time for the initiation of antiretroviral therapy for asymptomatic
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …

Survival benefit of initiating antiretroviral therapy in HIV-infected persons in different CD4+ cell strata

FJ Palella Jr, M Deloria-Knoll, JS Chmiel… - Annals of internal …, 2003 - acpjournals.org
Background: Optimal timing of antiretroviral therapy (ART) initiation for HIV-infected persons
remains unclear. Objective: To assess survival benefit of initiating ART at different CD4+ cell …

Initiation of antiretroviral therapy in early asymptomatic HIV infection

Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …

Mortality in HIV-seropositive versus-seronegative persons in the era of highly active antiretroviral therapy: implications for when to initiate therapy

C Wang, D Vlahov, N Galai, J Bareta… - The Journal of …, 2004 - academic.oup.com
Background. The optimal time to initiate highly active antiretroviral therapy (HAART) remains
unclear. Methods. Five hundred eighty-three human immunodeficiency virus (HIV) …

[HTML][HTML] Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies

When To Start Consortium - The Lancet, 2009 - Elsevier
BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be
started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of …

Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled …

B Grinsztejn, MC Hosseinipour, HJ Ribaudo… - The Lancet infectious …, 2014 - thelancet.com
Background Use of antiretroviral treatment for HIV-1 infection has decreased AIDS-related
morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to …

Low mortality in HIV-infected patients starting highly active antiretroviral therapy: a comparison with the general population

S Jensen-Fangel, L Pedersen, CS Larsen, P Tauris… - Aids, 2004 - journals.lww.com
Objectives: To assess the mortality in a cohort of HIV-infected patients starting highly active
antiretroviral therapy (HAART) compared to the mortality of the general population, focusing …

Prognostic importance of initial response in HIV-1 infected patients starting potent antiretroviral therapy: analysis of prospective studies

Antiretroviral Therapy (ART) Cohort Collaboration - The Lancet, 2003 - Elsevier
BACKGROUND: We examined whether the initial virological and immunological response to
highly active antiretroviral treatment (HAART) is prognostic in patients with HIV-1 who start …

Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies

M Egger, M May, G Chêne, AN Phillips, B Ledergerber… - The Lancet, 2002 - thelancet.com
Background Insufficient data are available from single cohort studies to allow estimation of
the prognosis of HIV-1 infected, treatment-naive patients who start highly active antiretroviral …

Immediate antiretroviral therapy decreases mortality among patients with high CD4 counts in China: a nationwide, retrospective cohort study

Y Zhao, Z Wu, JM McGoogan, CX Shi… - Clinical Infectious …, 2018 - academic.oup.com
Background Clinical trials have demonstrated that immediate initiation of antiretroviral
therapy (ART) reduces AIDS-related morbidity and mortality. We tested the hypothesis that …