In the last decade, the application of 2-photon intravital microscopy as a tool to study cell
interactions in different areas of the immune system has offered an unprecedented …

The efficient function of the immune system necessitates the complex interaction of antigens,
antigen-presenting cells, and cell populations that modulate, regulate and effectuate the …

The lymph nodes (LNs), spleen, and other secondary lymphoid organs (eg, Peyer's patches)
are strategically located in anatomical sites where they collect foreign antigen and antigen …

Lymphatic endothelial cells (LECs) form the structure of the lymphatic vessels and the
sinuses of the lymph nodes, positioning them to be key players in many different aspects of …

Afferent lymphatic vessels (LVs) mediate the transport of antigen and leukocytes to draining
lymph nodes (dLNs), thereby serving as immunologic communication highways between …

Lymphatic vessels are well known to participate in the immune response by providing the
structural and functional support for the delivery of antigens and antigen presenting cells to …

Naive T lymphocytes continuously recirculate through secondary lymphoid organs such as
lymph nodes until they are eventually activated by recognizing cognate peptide/MHC …

New preparations, fluorescent probes and imaging techniques are providing the means to
observe the behavior of cells in the tissue environment of lymphoid organs. In particular …

The organized accumulation of lymphocytes is a biological phenomenon used to optimize
both homeostatic immune surveillance, as well as chronic responses to pathogenic stimuli …

Genes tell lymphatics to sprout or not | Nature Immunology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …