Using microfluidics chips for live imaging and study of injury responses in Drosophila larvae

B Mishra, M Ghannad-Rezaie, J Li, X Wang… - JoVE (Journal of …, 2014 - jove.com
Live imaging is an important technique for studying cell biological processes, however this
can be challenging in live animals. The translucent cuticle of the Drosophila larva makes it …

Lab-on-a-chip technologies for manipulation and imaging of C. elegans worms and embryos

L Dong - 2018 - infoscience.epfl.ch
The nematode Caenorhabditis elegans is an attractive model organism, owing notably to its
short life cycle, genetic tractability, optical transparency facilitating microscopic observation …

High-throughput screening in the C. elegans nervous system

HE Kinser, Z Pincus - Molecular and Cellular Neuroscience, 2017 - Elsevier
The nematode Caenorhabditis elegans is widely used as a model organism in the field of
neurobiology. The wiring of the C. elegans nervous system has been entirely mapped, and …

Caenorhabditis elegans: A new model organism for studies of axon regeneration

A Ghosh‐Roy, AD Chisholm - Developmental dynamics: an …, 2010 - Wiley Online Library
Axonal regeneration in Caenorhabditis elegans was first reported five years ago. Individual
green fluorescent protein‐labeled axons can be severed using laser microsurgery and their …

Long-term imaging, automated high-content phenotyping and sorting of C. elegans larvae and embryos using microfluidic platforms

HB Atakan - 2019 - infoscience.epfl.ch
Résumé C. elegans is frequently studied to address fundamental biological questions
motivated by its short life cycle, small size, hermaphrodite behavior and well-annotated …

Caenorhabditis elegans-on-a-chip: microfluidic platforms for high-resolution imaging and phenotyping

S Mondal, A Ben-Yakar - Organ-on-a-chip, 2020 - Elsevier
Caenorhabditis elegans is an attractive alternative animal model for identifying toxicological
phenotypes in vivo, studying the mode of action of drugs, and characterizing physiological …

A microfabricated array of clamps for immobilizing and imaging C. elegans

SE Hulme, SS Shevkoplyas, J Apfeld, W Fontana… - Lab on a Chip, 2007 - pubs.rsc.org
This paper describes the fabrication of a microfluidic device for rapid immobilization of large
numbers of live C. elegans for performing morphological analysis, microsurgery, and …

Long-term culture and monitoring of isolated Caenorhabditis elegans on solid media in multi-well devices

EA Gardea, D DeNicola, S Freitas, W Peterson… - JoVE (Journal of …, 2022 - jove.com
The nematode Caenorhabditis elegans is among the most common model systems used in
aging research owing to its simple and inexpensive culture techniques, rapid reproduction …

Caenorhabditis sieve: A low-tech instrument and methodology for sorting small multicellular organisms

S Hunter, M Maulik, C Scerbak, E Vayndorf… - JoVE (Journal of …, 2018 - jove.com
Caenorhabditis elegans (C. elegans) is a well-established model organism used across a
range of basic and biomedical research. Within the nematode research community, there is …

Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans

CV Gabel, F Antoine, CF Chuang, ADT Samuel… - 2008 - journals.biologists.com
The molecular and cellular mechanisms that allow adult-stage neurons to regenerate
following damage are poorly understood. Recently, axons of motoneurons and …