Uptake and excretion of nutrients is an integral part of a cell's physiology. Using analytical
chemistry techniques, metabolite uptake and excretion from the culture medium can be …

Untargeted profiling of small-molecule metabolites from microbial culture supernatants
(metabolic footprinting) has great potential as a phenotyping tool. We used time-resolved …

Understanding metabolism is fundamental to access and harness bacterial physiology. In
most bacteria, nutrient utilization is hierarchically optimized according to their energetic …

Metabolomics embraces several strategies that aim to quantify cell metabolites in order to
increase our understanding of how metabolite levels and interactions influence phenotypes …

Background: Metabolomics aims to characterize the metabolic phenotype and metabolic
pathways utilized by microorganisms or other cellular systems. A crucial component to …

Bacterial populations exhibit a range of metabolic states influenced by their environment,
intra-and interspecies interactions. The identification of bacterial metabolic states and …

Gaining insight into the behavior of bacteria at the single-cell level is important given that
heterogeneous microenvironments strongly influence microbial physiology. The …

Metabolites give us a window into the chemistry of microbes and are split into two
subclasses: primary and secondary. Primary metabolites are required for life whereas …

Bacteria often reside in communities where the cells have secreted sticky, polymeric
compounds that allow them to attach to surfaces. This sessile lifestyle, referred to as a …

In addition to transcriptome and proteome studies, metabolome analysis represents a third
complementary approach to identify metabolic pathways and adaptation processes. In order …