Importance Cannabinoid drugs are widely used as analgesics, but experimental pain
studies have produced mixed findings. The analgesic properties of cannabinoids remain …

To date, a large number of controlled clinical trials have been done evaluating the
therapeutic applications of cannabis and cannabis-based preparations. In 2006, an …

Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

There is a growing use of novel psychoactive substances containing synthetic cannabinoids.
Synthetic cannabinoid products have effects similar to those of natural cannabis, yet, these …

Background Medicinal cannabinoids, including medicinal cannabis and pharmaceutical
cannabinoids and their synthetic derivatives, such as tetrahydrocannabinol (THC) and …

Purpose of review There have been many debates, discussions, and published writings
about the therapeutic value of cannabis plant and the hundreds of cannabinoids it contains …

Introduction The use of cannabis or cannabinoids to treat medical conditions and/or alleviate
symptoms is increasingly common. However, the impact of this use on patient reported …

Background Although cannabis and cannabinoids are widely used with therapeutic
purposes, their claimed efficacy is highly controversial. For this reason, medical cannabis …

There is growing interest in using cannabinoids for chronic pain. We performed a systematic
review and meta-analysis of randomized controlled trials to evaluate the analgesic efficacy …

Cannabis was extensively used as a medicine throughout the developed world in the
nineteenth century but went into decline early in the twentieth century ahead of its …