Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Nowadays, Cannabis sativa is considered the most extensively used narcotic. Nevertheless,
this fame obscures its traditional employ in native medicine of South Africa, South America …

The major psychoactive constituent of Cannabis sativa, Δ 9-tetrahydrocannabinol (Δ 9-THC),
and endogenous cannabinoid ligands, such as anandamide, signal through G-protein …

This study examines the current knowledge of physiological and clinical effects of
tetrahydrocannabinol (THC) and cannabidiol (CBD) and presents a rationale for their …

Neuropathic pain is a worldwide epidemic that occurs in 3 to 8% of individuals in
industrialized countries and is often refractory to existing treatments. Drugs currently …

OBJECTIVE: To systematically review published reports to identify the evidence base of
cannabinoids as a medical treatment in children and adolescents. DATA SOURCES: Based …

Objective: Two primary compounds of the cannabis plant (Cannabis sativa), delta-9-
tetrahydrocannabinol (THC) and cannabidiol (CBD), differentially and dose-dependently …

Objective Cannabidiol (CBD) has a proposed novel role in the management of anxiety
owing to its actions on the endocannabinoid system. The purpose of this systematic review …

We provide a systematic review and meta‐analysis on the efficacy, tolerability, and safety of
cannabinoids in palliative medicine. The Cochrane Central Register of Controlled Trials …

Cannabinoids bind not only to classical receptors (CB1 and CB2) but also to certain orphan
receptors (GPR55 and GPR119), ion channels (transient receptor potential vanilloid), and …