Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …
Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain
The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …
tightly controls the transport of materials between the blood and the brain. There is an …
Strategies for transporting nanoparticles across the blood–brain barrier
The existence of blood–brain barrier (BBB) hampers the effective treatment of central
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …
Drug delivery to the brain across the blood–brain barrier using nanomaterials
A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …
Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: at a glance
MM Rhaman, MR Islam, S Akash, M Mim… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …
placed a strong emphasis on cutting-edge nanostructured materials technologies to …
Nanoscale drug delivery systems and the blood–brain barrier
The protective properties of the blood–brain barrier (BBB) are conferred by the intricate
architecture of its endothelium coupled with multiple specific transport systems expressed on …
architecture of its endothelium coupled with multiple specific transport systems expressed on …
Recent advancements of nanomedicine in neurodegenerative disorders theranostics
S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …
Nanoparticle transport across the blood brain barrier
AM Grabrucker, B Ruozi, D Belletti, F Pederzoli… - Tissue …, 2016 - Taylor & Francis
While the role of the blood-brain barrier (BBB) is increasingly recognized in the
(development of treatments targeting neurodegenerative disorders, to date, few strategies …
(development of treatments targeting neurodegenerative disorders, to date, few strategies …
Neurological disorders and therapeutics targeted to surmount the blood–brain barrier
We are now in an aging population, so neurological disorders, particularly the
neurodegenerative diseases, are becoming more prevalent in society. As per the …
neurodegenerative diseases, are becoming more prevalent in society. As per the …
Nanomaterials for drug delivery to the central nervous system
The intricate microstructure of the blood-brain barrier (BBB) is responsible for the accurate
intrinsic regulation of the central nervous system (CNS), in terms of neuronal …
intrinsic regulation of the central nervous system (CNS), in terms of neuronal …