Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS

GA Silva - BMC neuroscience, 2008 - Springer
Nanotechnologies are materials and devices that have a functional organization in at least
one dimension on the nanometer (one billionth of a meter) scale, ranging from a few to …

Novel nanomaterials for clinical neuroscience

JL Gilmore, X Yi, L Quan, AV Kabanov - Journal of NeuroImmune …, 2008 - Springer
Neurodegenerative disorders including Alzheimer's and Parkinson's diseases, amyotrophic
lateral sclerosis, and stroke are rapidly increasing as population ages. The field of …

Advances in nanomedicines for diagnosis of central nervous system disorders

X Zhang, J Zhou, Z Gu, H Zhang, Q Gong, K Luo - Biomaterials, 2021 - Elsevier
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

Nanotechnology—novel therapeutics for CNS disorders

M Srikanth, JA Kessler - Nature reviews neurology, 2012 - nature.com
Research into treatments for diseases of the CNS has made impressive strides in the past
few decades, but therapeutic options are limited for many patients with CNS disorders …

Nanoparticles in the treatment and diagnosis of neurological disorders: untamed dragon with fire power to heal

JR Kanwar, X Sun, V Punj, B Sriramoju… - … , Biology and Medicine, 2012 - Elsevier
The incidence of neurological diseases of unknown etiology is increasing, including well-
studied diseases such as Alzhiemer's, Parkinson's, and multiple sclerosis. The blood-brain …

Delivery of nanoparticles and macromolecules across the blood–brain barrier

M Nowak, ME Helgeson, S Mitragotri - Advanced Therapeutics, 2020 - Wiley Online Library
Abstract Treatment of brain‐related diseases is challenging due to the presence of the blood–
brain barrier (BBB), a hurdle that prevents most foreign matter from entering the brain. While …

[HTML][HTML] Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases

HE Gendelman, V Anantharam, T Bronich… - … , Biology and Medicine, 2015 - Elsevier
Interest in nanoneuromedicine has grown rapidly due to the immediate need for improved
biomarkers and therapies for psychiatric, developmental, traumatic, inflammatory, infectious …

Therapeutic nanoplatforms and delivery strategies for neurological disorders

YJ Kang, EG Cutler, H Cho - Nano Convergence, 2018 - Springer
The major neurological disorders found in a central nervous system (CNS), such as brain
tumors, Alzheimer's diseases, Parkinson's diseases, and Huntington's disease, have led to …

Nanostructures: a platform for brain repair and augmentation

R Vidu, M Rahman, M Mahmoudi… - Frontiers in systems …, 2014 - frontiersin.org
Nanoscale structures have been at the core of research efforts dealing with integration of
nanotechnology into novel electronic devices for the last decade. Because the size of …

Nanocarriers as potential drug delivery candidates for overcoming the blood–brain barrier: challenges and possibilities

J Ahlawat, G Guillama Barroso, S Masoudi Asil… - Acs Omega, 2020 - ACS Publications
The design of a drug that successfully overcomes the constraints imposed by the blood–
brain barrier (BBB, which acts as a gatekeeper to the entry of substances into the brain) …