Therapeutic benefits from nanoparticles: the potential significance of nanoscience in diseases with compromise to the blood brain barrier
S Krol, R Macrez, F Docagne, G Defer… - Chemical …, 2013 - ACS Publications
Nanotechnology is an area of growing public interest. Its attractiveness stems from the
promise offered socially and economically by the recent significant advances in …
promise offered socially and economically by the recent significant advances in …
Nanobiotechnology-based strategies for crossing the blood–brain barrier
KK Jain - Nanomedicine, 2012 - Taylor & Francis
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it
also significantly hinders the delivery of therapeutics to the brain. Several strategies have …
also significantly hinders the delivery of therapeutics to the brain. Several strategies have …
Targeted delivery of nano-therapeutics for major disorders of the central nervous system
Major central nervous system (CNS) disorders, including brain tumors, Alzheimer's disease,
Parkinson's disease, and stroke, are significant threats to human health. Although …
Parkinson's disease, and stroke, are significant threats to human health. Although …
Modern methods for delivery of drugs across the blood–brain barrier
Y Chen, L Liu - Advanced drug delivery reviews, 2012 - Elsevier
The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …
[HTML][HTML] Current strategies to enhance delivery of drugs across the blood–brain barrier
RI Teleanu, MD Preda, AG Niculescu, O Vladâcenco… - Pharmaceutics, 2022 - mdpi.com
The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …
Therapeutics, imaging and toxicity of nanomaterials in the central nervous system
A Nunes, KT Al-Jamal, K Kostarelos - Journal of Controlled Release, 2012 - Elsevier
Treatment and diagnosis of neurodegenerative diseases and other CNS disorders are
nowadays considered some of the most challenging tasks in modern medicine. The …
nowadays considered some of the most challenging tasks in modern medicine. The …
Overcoming blood–brain barrier transport: Advances in nanoparticle-based drug delivery strategies
The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …
protects the brain from bloodborne pathogens by its excellent barrier properties …
[HTML][HTML] Nanoparticle-based technology approaches to the management of neurological disorders
Neurological disorders are the most devastating and challenging diseases associated with
the central nervous system (CNS). The blood-brain barrier (BBB) maintains homeostasis of …
the central nervous system (CNS). The blood-brain barrier (BBB) maintains homeostasis of …
Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system
GA Silva - Surgical Neurology, 2005 - Elsevier
Nanotechnology is the science and engineering concerned with the design, synthesis, and
characterization of materials and devices that have a functional organization in at least 1 …
characterization of materials and devices that have a functional organization in at least 1 …
[HTML][HTML] Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases
The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …
blood. The BBB's unique and protective features control brain homeostasis as well as ion …