The development of drugs to treat disorders of the central nervous system (CNS) faces
difficulties in achieving penetration of a drug through the blood–brain barrier (BBB) and …

Neurodegenerative disorders (NDs) are highly prevalent among the aging population. It
affects primarily the central nervous system (CNS) but the effects are also observed in the …

Neurodegenerative and infectious disorders including Alzheimer's and Parkinson's
diseases, amyotrophic lateral sclerosis, and stroke are rapidly increasing as population's …

Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

Nanotechnology is the science and engineering concerned with the design, synthesis, and
characterization of materials and devices that have a functional organization in at least one …

Alzheimer's disease (AD) is a progressive deterioration of brain function, initially
characterized by cognitive deficits, with loss of recent memory and language ability …

Therapies targeting neurological conditions such as Alzheimer's or Parkinson's diseases are
hampered by the presence of the blood-brain barrier (BBB). During the last decades, several …

Nanotechnologies exploit materials and devices with a functional organization that has been
engineered at the nanometre scale. The application of nanotechnology in cell biology and …

With an increase in lifespan and changing population demographics, the incidence of
central nervous system (CNS) diseases is expected to increase significantly in the 21st …

The efficacy, cellular uptake and specific transport of drugs and/or imaging agents to target
organs, tissues and cells are common issues in the diagnosis and treatment of different …