The mechanisms through which maternal immunization can modulate offspring thymic
maturation of lymphocytes are not fully understood. Here, we aimed to evaluate whether …

Abstract IgG4-related disease (IgG4-RD) is characterized by intense infiltration of IgG4-
positive plasma cells in affected organs. However, the mechanisms acting in the immune …

Background The pathogenetic mechanisms of neutrophilic asthma are not well understood
now. Whether T helper (Th) 17-mediated immunity contributes to the pathogenesis of …

Our aims were to identify the differential expression of microRNA (miR)-155, as well as to
explore the possible regulatory effects of miR-155 on the differentiation and function of T …

Various populations of effector and regulatory T (Treg) cells have been shown to play a
central role in chronic inflammation in various diseases, the maintenance of peripheral …

Recent evidence has suggested that microRNAs (miRNAs) may play a significant role in the
pathogenesis of inflammatory skin conditions such as atopic dermatitis (AD). The aim of the …

TH17 and Treg cells have a reciprocal development pathway. 5 Both cells play an important
role in the induction and perpetuation of inflammatory responses during infection, and also …

Purpose Allergen exposure induces aberrant T helper (Th) 2 immune responses in patients
with allergic asthma, but not in sensitized asymptomatic and nonallergic subjects. Interleukin …

Purpose Regulatory T (Treg) cells are key modulators in the immune system. Recent studies
have shown that atopic dermatitis (AD) patients have higher numbers of Treg cells; however …

Background Protection against helminths consists of adaptive responses by TH 2 cells and
innate responses by group 2 innate lymphoid cells (ILC2s), with these latter being well …