WTAP participates in neuronal damage by protein translation of NLRP3 in an m6A-YTHDF1-dependent manner after traumatic brain injury
Y Chen, T Long, J Chen, H Wei, J Meng… - International Journal of … - journals.lww.com
Background Traumatic brain injury (TBI) is a common complication of acute and severe
neurosurgery. Remodeling of N6-methyladenosine (m6A) stabilization may be an attractive …
neurosurgery. Remodeling of N6-methyladenosine (m6A) stabilization may be an attractive …
Silencing of YTHDF1 attenuates cerebral stroke by inducing PTEN degradation and activating the PTEN/AKT/mTOR pathway
X Li, P An, F Han, M Yu, Z Yu, Y Li - Molecular biotechnology, 2023 - Springer
Abstract N6-methyladenosine (m6A) methylation regulates pathological processes of
cerebral stroke, which can lead to disability and death. Herein, we explored the role of a …
cerebral stroke, which can lead to disability and death. Herein, we explored the role of a …
METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke
W Su, X Yu, S Wang, X Wang, Z Dai, Y Li - Cell biology and toxicology, 2024 - Springer
Background Stroke is a major medical problem, and novel therapeutic targets are urgently
needed. This study investigates the protective role and potential mechanisms of the N6 …
needed. This study investigates the protective role and potential mechanisms of the N6 …
USP1/UAF1-stabilized METTL3 promotes reactive astrogliosis and improves functional recovery after spinal cord injury through m6A modification of YAP1 mRNA
X Ge, W Ye, Y Zhu, M Cui, J Zhou, C Xiao… - Journal of …, 2023 - Soc Neuroscience
RNA N6-methyladenosine (m6A) modification is involved in diverse biological processes.
However, its role in spinal cord injury (SCI) is poorly understood. The m6A level increases in …
However, its role in spinal cord injury (SCI) is poorly understood. The m6A level increases in …
The m6A methyltransferase METTL3 drives neuroinflammation and neurotoxicity through stabilizing BATF mRNA in microglia
X Wu, H Liu, J Wang, S Zhang, Q Hu, T Wang… - Cell Death & …, 2024 - nature.com
Persistent neuroinflammation and progressive neuronal loss are defining features of acute
brain injury including traumatic brain injury (TBI) and cerebral stroke. Microglia, the most …
brain injury including traumatic brain injury (TBI) and cerebral stroke. Microglia, the most …
Methylated MFGE8 Promotes Early Brain Injury After Subarachnoid Hemorrhage and Inhibiting Autophagy of Nerve Cell
L Zou, S Xu, C Wang, P Wu, C Xu, H Shi - Translational Stroke Research, 2023 - Springer
Background Spontaneous subarachnoid hemorrhage (SAH) is a relatively common clinical
hemorrhagic stroke crisis. The important role of early brain injury (EBI) and autophagy in …
hemorrhagic stroke crisis. The important role of early brain injury (EBI) and autophagy in …
LncRNA TUG1 demethylated by TET2 promotes NLRP3 expression, contributes to cerebral ischemia/reperfusion inflammatory injury
M Yin, WP Chen, XP Yin, JL Tu, N Hu, ZY Li - ASN neuro, 2021 - journals.sagepub.com
LncRNA TUG1 has not yet been reported in cerebral ischemia/reperfusion (I/R) injury.
Methylcytosine dioxygenase TET2 is involved in ischemic damage. This study aimed to …
Methylcytosine dioxygenase TET2 is involved in ischemic damage. This study aimed to …
Demethylase FTO-mediated m6A modification of lncRNA MEG3 activates neuronal pyroptosis via NLRP3 signaling in cerebral ischemic stroke
H Yan, W Huang, J Rao, D Yan, J Yuan - Molecular Neurobiology, 2024 - Springer
Neuronal death following ischemia is the primary cause of death and disability in patients
with ischemic stroke. N6-methyladenosine (m6A) modification plays essential role in various …
with ischemic stroke. N6-methyladenosine (m6A) modification plays essential role in various …
Transcription Factor TFAP2B Exerts Neuroprotective Effects Targeting BNIP3-Mediated Mitophagy in Ischemia/Reperfusion Injury
Y Peng, J Jia, M Zhang, W Ma, Y Cui, M Yu - Molecular Neurobiology, 2024 - Springer
Cerebral ischemia–reperfusion injury (CIRI) leads to malignant brain edema, blood–brain
barrier destruction, and neuronal apoptosis. N6-methyladenosine (m6A) RNA modification …
barrier destruction, and neuronal apoptosis. N6-methyladenosine (m6A) RNA modification …
N6-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury
K Xu, Y Mo, D Li, Q Yu, L Wang, F Lin… - … advances in chronic …, 2020 - journals.sagepub.com
Background: Although N6-methyladenosine (m6A) plays a very important role in different
biological processes, its function in the brain has not been fully explored. Thus, we …
biological processes, its function in the brain has not been fully explored. Thus, we …
相关搜索
- neuronal damage protein translation
- m6a ythdf1 protein translation
- m6a ythdf1 neuronal damage
- m6a ythdf1 brain injury
- brain injury protein translation
- brain injury neuronal damage
- brain injury subarachnoid hemorrhage
- inflammatory injury nlrp3 expression
- brain injury nerve cell
- functional recovery m6a modification
- functional recovery cord injury
- functional recovery reactive astrogliosis
- ischemia reperfusion n6 methyladenosine
- neuronal pyroptosis m6a modification
- cord injury m6a modification