Current models of B lymphocyte biology posit that B cells continuously recirculate between
lymphoid organs, without accumulating in peripheral healthy tissues. Nevertheless, B …

The uninjured murine heart contains a heterogeneous population of macrophages with
disparate ontogenies and functions. These macrophages are often associated with blood …

B cells are traditionally known for their ability to produce antibodies in the context of adaptive
immune responses. However, over the last decade B cells have been increasingly …

Abstract Purpose of Review To summarize the current knowledge on the role that B
lymphocytes play in heart failure. Recent Findings Several studies from murine models have …

Aims Recent studies have revealed that B cells and antibodies can influence inflammation
and remodelling following a myocardial infarction (MI) and culminating in heart failure—but …

A robust, sterile inflammation underlies myocardial ischemia and reperfusion injury (MIRI).
Several subsets of B cells possess the immunoregulatory capacity that limits tissue damage …

Introduction The mammalian adult heart maintains a continuous, low cardiomyocyte turnover
rate throughout life. Although many cardiac stem cell populations have been studied, the …

Atherosclerosis is a lipid-driven inflammatory disease of blood vessels, and both innate and
adaptive immune responses are involved in its development. The impact of B cells on …

The lymphatic vasculature has an essential role in maintaining normal fluid balance in
tissues and modulating the inflammatory response to injury or pathogens. Disruption of …

Aims Several cardiac resident progenitor cell types have been reported for the adult
mammalian heart. Here we characterize their frequencies and distribution pattern in non …