Free fatty acids (FFAs) are energy substrates for many cell types, but in excess, some FFAs
can accumulate in nonadipose cells, inducing apoptosis. Also known as lipotoxicity, this …

Obesity is associated with altered fatty acid profiles, reduced fertility, and assisted
reproductive technology (ART) success. The effects of palmitic acid (PA), oleic acid (OA) …

Pre-pregnancy body mass index determines pregnancy outcome (Nelson et al. 2010, Flegal
et al. 2012), and more than half of pregnant women in the United States are overweight or …

Introduction Obesity during pregnancy increases the risk for maternal complications like
gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also …

Background Our objective was to determine the effect of fatty acids (FAs) in serum and
follicular fluid (FF) on fertilization and intracytoplasmic sperm injection (ICSI) outcomes …

Maternal metabolic disorders may cause lipotoxic effects on the developing oocyte.
Understanding the timing at which this might disrupt embryo epigenetic programming and …

Maternal obesity increases the risk of childhood obesity and programs the offspring to
develop metabolic syndrome later in their life. Palmitate is the predominant saturated free …

Growing evidence suggests that endogenous and exogenous fatty acids play diverse roles
in developing mammalian oocytes and early embryos. In this review, we describe some of …

The fetus is dependent on delivery of fatty acids (FAs) by the syncytiotrophoblast, the
transporting epithelium of the human placenta. Obese pregnant women have dyslipidemia; …

Background/Aims: The omega 6 fatty acid (FA) linoleic acid (LA) is required for embryonic
development; however, omega 6 FAs can alter cellular metabolism via inflammation or …