[HTML][HTML] Synthesis of functionalized 10-nm polymer-coated gold particles for endothelium targeting and drug delivery

MJ Cheng, P Prabakaran, R Kumar… - Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) have been used extensively in medical research due to their
size, biocompatibility, and modifiable surface. Specific targeting and drug delivery are some …

Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial …

T Mohamed, S Matou-Nasri, A Farooq… - International journal …, 2017 - Taylor & Francis
Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …

Gold nanoparticle interactions with endothelial cells cultured under physiological conditions

C Freese, L Anspach, RC Deller, SJ Richards… - Biomaterials …, 2017 - pubs.rsc.org
PEGylated gold nanoparticles (AuNPs) have an extended circulation time after intravenous
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …

Size-and coating-dependent uptake of polymer-coated gold nanoparticles in primary human dermal microvascular endothelial cells

C Freese, MI Gibson, HA Klok, RE Unger… - …, 2012 - ACS Publications
A library-orientated approach is used to gain understanding of the interactions of well-
defined nanoparticles with primary human endothelial cells, which are a key component of …

[HTML][HTML] Surface functionalization of gold nanoparticles with red blood cell membranes

W Gao, CMJ Hu, RH Fang, BT Luk, J Su… - … (Deerfield Beach, Fla.), 2013 - ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) find widespread applications as imaging agents and drug
carriers in biology and medicine owing to their biocompatibility, optical properties, and easily …

Uptake of poly (2-hydroxypropylmethacrylamide)-coated gold nanoparticles in microvascular endothelial cells and transport across the blood–brain barrier

C Freese, RE Unger, RC Deller, MI Gibson… - Biomaterials …, 2013 - pubs.rsc.org
The facile and modular functionalization of gold nanoparticles makes them versatile tools in
nanomedicine, for instance, photothermal therapy, contrast agents or as model …

Uptake of gold nanoparticles in primary human endothelial cells

H Klingberg, LB Oddershede, K Loeschner… - Toxicology …, 2015 - academic.oup.com
Gold nanoparticles (AuNPs) are relevant in nanomedicine for drug delivery in the vascular
system, where endothelial cells are the first point of contact. We investigated the uptake of …

Ultrasmall gold nanorods: synthesis and glycocalyx-related permeability in human endothelial cells

MJ Cheng, NN Bal, P Prabakaran… - International Journal …, 2019 - Taylor & Francis
Background Clinical data show shed endothelial glycocalyx (GCX) components in blood
samples of atherosclerotic patients, linking atherosclerotic development to endothelial GCX …

Manipulation of in Vitro Angiogenesis Using Peptide-Coated Gold Nanoparticles

D Bartczak, OL Muskens, T Sanchez-Elsner… - ACS …, 2013 - ACS Publications
We demonstrate the deliberate activation or inhibition of in vitro angiogenesis using
functional peptide coated gold nanoparticles. The peptides, anchored to oligo-ethylene …

Enhanced penetration into 3D cell culture using two and three layered gold nanoparticles

CG England, T Priest, G Zhang, X Sun… - International journal …, 2013 - Taylor & Francis
Nano-scale particles sized 10–400 nm administered systemically preferentially extravasate
from tumor vasculature due to the enhanced permeability and retention effect. Therapeutic …