[HTML][HTML] Reproducible model development in the cardiac electrophysiology Web Lab
The modelling of the electrophysiology of cardiac cells is one of the most mature areas of
systems biology. This extended concentration of research effort brings with it new …
systems biology. This extended concentration of research effort brings with it new …
The cardiac electrophysiology web lab
Computational modeling of cardiac cellular electrophysiology has a long history, and many
models are now available for different species, cell types, and experimental preparations …
models are now available for different species, cell types, and experimental preparations …
High-throughput functional curation of cellular electrophysiology models
Effective reuse of a quantitative mathematical model requires not just access to curated
versions of the model equations, but also an understanding of the functional capabilities of …
versions of the model equations, but also an understanding of the functional capabilities of …
Considerations for the use of cellular electrophysiology models within cardiac tissue simulations
The use of mathematical models to study cardiac electrophysiology has a long history, and
numerous cellular scale models are now available, covering a range of species and cell …
numerous cellular scale models are now available, covering a range of species and cell …
Cell-specific cardiac electrophysiology models
W Groenendaal, FA Ortega… - PLoS computational …, 2015 - journals.plos.org
The traditional cardiac model-building paradigm involves constructing a composite model
using data collected from many cells. Equations are derived for each relevant cellular …
using data collected from many cells. Equations are derived for each relevant cellular …
Cardiac cell modelling: observations from the heart of the cardiac physiome project
In this manuscript we review the state of cardiac cell modelling in the context of international
initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim …
initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim …
[HTML][HTML] The Noble cardiac ventricular electrophysiology models in CellML
DP Nickerson, PJ Hunter - Progress in biophysics and molecular biology, 2006 - Elsevier
We present a review of the cardiac ventricular cell electrophysiology models developed by
Prof. Denis Noble and colleagues as an example of how models may be published using a …
Prof. Denis Noble and colleagues as an example of how models may be published using a …
From single myocyte to whole heart: the intricate dance of electrophysiology and modeling
S Despa, E Vigmond - Circulation research, 2016 - Am Heart Assoc
Despa and Vigmond Whole-Heart Electrophysiology and Modeling 185 conclusion was
supported by the observation that slowing down the rate of Phase-1 repolarization by …
supported by the observation that slowing down the rate of Phase-1 repolarization by …
[HTML][HTML] Rabbit-specific computational modelling of ventricular cell electrophysiology: Using populations of models to explore variability in the response to ischemia
P Gemmell, K Burrage, B Rodríguez… - Progress in biophysics and …, 2016 - Elsevier
Computational modelling, combined with experimental investigations, is a powerful method
for investigating complex cardiac electrophysiological behaviour. The use of rabbit-specific …
for investigating complex cardiac electrophysiological behaviour. The use of rabbit-specific …
From millimeters to micrometers; re-introducing myocytes in models of cardiac electrophysiology
Computational modeling has contributed significantly to present understanding of cardiac
electrophysiology including cardiac conduction, excitation-contraction coupling, and the …
electrophysiology including cardiac conduction, excitation-contraction coupling, and the …