Pirfenidone accelerates wound healing in chronic diabetic foot ulcers: a randomized, double‐blind controlled trial
LE Gasca-Lozano, S Lucano-Landeros… - Journal of diabetes …, 2017 - Wiley Online Library
Background. Diabetic foot ulcers are one disabling complication of diabetes mellitus.
Pirfenidone (PFD) is a potent modulator of extracellular matrix. Modified diallyl disulfide …
Pirfenidone (PFD) is a potent modulator of extracellular matrix. Modified diallyl disulfide …
Topical administration of pirfenidone increases healing of chronic diabetic foot ulcers: a randomized crossover study
M Janka-Zires, P Almeda-Valdes… - Journal of Diabetes …, 2016 - Wiley Online Library
Only 30 percent of chronic diabetic foot ulcers heal after 20 weeks of standard treatment.
Pirfenidone is a drug with biological, anti‐inflammatory, and antifibrotic effects. The aim of …
Pirfenidone is a drug with biological, anti‐inflammatory, and antifibrotic effects. The aim of …
Mechanisms involved in the development and healing of diabetic foot ulceration
T Dinh, F Tecilazich, A Kafanas, J Doupis… - Diabetes, 2012 - Am Diabetes Assoc
We examined the role of vascular function and inflammation in the development and failure
to heal diabetic foot ulcers (DFUs). We followed 104 diabetic patients for a period of …
to heal diabetic foot ulcers (DFUs). We followed 104 diabetic patients for a period of …
Physiological and Pathophysiological Aspects of Diabetic Foot Ulcer and its Treatment Strategies
V Ramachandran, T Mohanasundaram… - Current Diabetes …, 2023 - ingentaconnect.com
Background: Diabetes foot ulcers (DFU) are among the most common complications in
diabetic patients, leading to amputation and psychological distress. This mini-review covers …
diabetic patients, leading to amputation and psychological distress. This mini-review covers …
Phase I trial on the safety of topical rhVEGF on chronic neuropathic diabetic foot ulcers
JR Hanft, RA Pollak, A Barbul, C Gils… - Journal of wound …, 2008 - magonlinelibrary.com
Objective: To assess the safety/tolerability and perform a preliminary efficacy evaluation of a
multiple-dosing regimen of recombinant human vascular endothelial growth factor …
multiple-dosing regimen of recombinant human vascular endothelial growth factor …
Pharmaceutical perspectives of impaired wound healing in diabetic foot ulcer
HC Lau, A Kim - Journal of Pharmaceutical Investigation, 2016 - Springer
Abstract Treatment for diabetic foot ulcer (DFU) remains as one of the biggest clinical
concerns in diabetic disease. DFU often causes a prolonged treatment and eventually leads …
concerns in diabetic disease. DFU often causes a prolonged treatment and eventually leads …
Epidermal growth factor is effective in the treatment of diabetic foot ulcers: meta-analysis and systematic review
Diabetic foot ulcers (DFUs) are one the common complications of diabetes mellitus. Many
trials were performed to evaluate the effect of recombinant human epidermal growth factor …
trials were performed to evaluate the effect of recombinant human epidermal growth factor …
Current status and progress in research on dressing management for diabetic foot ulcer
P Jiang, Q Li, Y Luo, F Luo, Q Che, Z Lu… - Frontiers in …, 2023 - frontiersin.org
Diabetic foot ulcer (DFU) is a major complication of diabetes and is associated with a high
risk of lower limb amputation and mortality. During their lifetime, 19%–34% of patients with …
risk of lower limb amputation and mortality. During their lifetime, 19%–34% of patients with …
Effects of vildagliptin on wound healing and markers of inflammation in patients with type 2 diabetic foot ulcer: a prospective, randomized, double-blind, placebo …
VN Vangaveti, S Jhamb, O Hayes, J Goodall… - Diabetology & Metabolic …, 2022 - Springer
Introduction Diabetic foot ulcers (DFU) are one of the leading long-term complications
experienced by patients with diabetes. Dipeptidyl Peptidase 4 inhibitors (DPP4is) are a …
experienced by patients with diabetes. Dipeptidyl Peptidase 4 inhibitors (DPP4is) are a …
[HTML][HTML] Diabetic foot ulcer: Challenges and future
L Yang, GC Rong, QN Wu - World journal of diabetes, 2022 - ncbi.nlm.nih.gov
Diabetic foot ulcers (DFUs) have become one of the important causes of mortality and
morbidity in patients with diabetes, and they are also a common cause of hospitalization …
morbidity in patients with diabetes, and they are also a common cause of hospitalization …