Comparison of 2 Anti-PLA2R Immunoassays for the Diagnosis of Primary Membranous Nephropathy

W Li, Y Guo, Z Zhang, F Zhang, X Liu, X Ji… - Laboratory …, 2018 - academic.oup.com
Background Anti–phospholipase A2 receptor (anti-PLA2R) is a promising biomarker for
diagnosis, activity evaluation, therapy monitoring, and prognostic estimation of primary …

Serum anti-PLA2R antibody as a diagnostic biomarker of idiopathic membranous nephropathy: the optimal cut-off value for Chinese patients

Y Liu, X Li, C Ma, P Wang, J Liu, H Su, H Zhuo… - Clinica Chimica …, 2018 - Elsevier
Background The M-type phospholipase A2 receptor (PLA2R) is a specific target autoantigen
identified in idiopathic membranous nephropathy (IMN). The autoantibody against PLA2R …

Clinical value of a serum anti-PLA2R antibody in the diagnosis and monitoring of primary membranous nephropathy in adults

X Wu, L Liu, Y Guo, L Yang - International journal of nephrology …, 2018 - Taylor & Francis
Objective To compare the positive rate of anti-PLA2R antibodies in patients with primary
membranous nephropathy (PMN), secondary membranous nephropathy (SMN), and non …

[HTML][HTML] The prognostic value of anti-PLA2R antibodies levels in primary membranous nephropathy

OL Kukuy, R Cohen, B Gilburd, E Zeruya… - International Journal of …, 2023 - mdpi.com
Anti-PLA2R antibodies (Ab) are a diagnostic and prognostic biomarker in primary
membranous nephropathy (PMN). We assessed the relationship between the levels of anti …

[HTML][HTML] The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy

D Bajcsi, L Bitó, S Turkevi-Nagy, T Nyári, É Kemény… - BMC nephrology, 2023 - Springer
Background The diagnostic performance of PLA2R and IgG subclass staining of kidney
biopsies relative to anti-PLA2R seropositivity in the differentiation of primary and secondary …

Optimal value for serum anti-PLA2R antibody in primary membranous nephropathy: a multicenter observational study

J Chen, X Jia, X Wei, J Li, Y Liu, Y Lian, Z Cui… - American Journal of …, 2022 - karger.com
Introduction: Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is highly specific for
primary membranous nephropathy (PMN). Here, we compare the diagnostic value of …

Evaluation of anti-PLA2R1 as measured by a novel ELISA in patients with idiopathic membranous nephropathy: a cohort study

SA Timmermans, JGMC Damoiseaux… - American journal of …, 2014 - academic.oup.com
Objectives: Autoantibodies against the M-type phospholipase A2 receptor 1 (anti-PLA2R1)
have been demonstrated to be very specific for idiopathic membranous nephropathy (MN) …

Quantitative detection of anti-PLA2R antibodies targeting different epitopes and its clinical application in primary membranous nephropathy

Y Qin, Q Wu, H Sheng, T Li, X Liu, X Yang… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives This study aimed to establish time-resolved fluorescence immunoassays to
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …

Preliminary results of research on a new marker of idiopathic membranous nephropathy: anti-PLA2R

M Kozioł, A Sikora, M Kozioł-Montewka… - Polski merkuriusz …, 2014 - europepmc.org
Results Antibodies were detected in 12 patients (54.54%): diagnosed (n= 5) and monitor (n=
7). All of patients with exacerbated disease process in monitored group had positive test …

[HTML][HTML] Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?

O Ragy, V Rautemaa, A Smith, P Brenchley… - PLoS …, 2023 - journals.plos.org
Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology
practice has not changed dramatically, with most nephrologists still relying on a kidney …