Effects of empagliflozin on risk for cardiovascular death and heart failure hospitalization across the spectrum of heart failure risk in the EMPA-REG OUTCOME® trial
D Fitchett, J Butler, P van de Borne… - European heart …, 2018 - academic.oup.com
Aims Empagliflozin reduced the risk of cardiovascular (CV) death and heart failure (HF)
hospitalizations in patients with type 2 diabetes (T2D) and established CV disease (CVD) in …
hospitalizations in patients with type 2 diabetes (T2D) and established CV disease (CVD) in …
Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME® trial
Aims We previously reported that in the EMPA-REG OUTCOME® trial, empagliflozin added
to standard of care reduced the risk of 3-point major adverse cardiovascular events …
to standard of care reduced the risk of 3-point major adverse cardiovascular events …
Empagliflozin reduced mortality and hospitalization for heart failure across the spectrum of cardiovascular risk in the EMPA-REG OUTCOME trial
D Fitchett, SE Inzucchi, CP Cannon, DK McGuire… - Circulation, 2019 - Am Heart Assoc
Background: In the EMPA-REG OUTCOME trial (BI 10773 [Empagliflozin] Cardiovascular
Outcome Event Trial in Type 2 Diabetes Mellitus Patients) in patients with type 2 diabetes …
Outcome Event Trial in Type 2 Diabetes Mellitus Patients) in patients with type 2 diabetes …
Mediators of the improvement in heart failure outcomes with empagliflozin in the EMPA‐REG OUTCOME trial
D Fitchett, SE Inzucchi, B Zinman, C Wanner… - ESC Heart …, 2021 - Wiley Online Library
Abstract Aims In the EMPA‐REG OUTCOME trial, empagliflozin reduced risk of death from
heart failure (HF) or hospitalization for heart failure (HHF) versus placebo in patients with …
heart failure (HF) or hospitalization for heart failure (HHF) versus placebo in patients with …
Efficacy of empagliflozin in patients with heart failure across kidney risk categories
Background Empagliflozin reduces the risk of major heart failure outcomes in heart failure
with reduced or preserved ejection fraction. Objectives The goal of this study was to evaluate …
with reduced or preserved ejection fraction. Objectives The goal of this study was to evaluate …
Effect of empagliflozin on cardiovascular and renal outcomes in patients with heart failure by baseline diabetes status: results from the EMPEROR-reduced trial
Background: Sodium-glucose cotransporter 2 inhibitors improve outcomes in patients with
heart failure with reduced ejection fraction, but additional information is needed about …
heart failure with reduced ejection fraction, but additional information is needed about …
How does empagliflozin reduce cardiovascular mortality? Insights from a mediation analysis of the EMPA-REG OUTCOME trial
SE Inzucchi, B Zinman, D Fitchett, C Wanner… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE In the BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2
Diabetes Mellitus Patients (EMPA-REG OUTCOME) trial involving 7,020 patients with type 2 …
Diabetes Mellitus Patients (EMPA-REG OUTCOME) trial involving 7,020 patients with type 2 …
Empagliflozin and the risk of heart failure hospitalization in routine clinical care: a first analysis from the EMPRISE study
Background: The EMPA-REG OUTCOME trial (Empagliflozin Cardiovascular Outcome Event
Trial in Type 2 diabetes Mellitus Patients) showed that empagliflozin, a sodium-glucose …
Trial in Type 2 diabetes Mellitus Patients) showed that empagliflozin, a sodium-glucose …
Empagliflozin Improves Kidney Outcomes in Patients With or Without Heart Failure: Insights From the EMPA-REG OUTCOME Trial
Background: In EMPA-REG OUTCOME (Empagliflozin Cardiovascular Outcome Event Trial
in Type 2 Diabetes Mellitus Patients) empagliflozin significantly reduced the risk of …
in Type 2 Diabetes Mellitus Patients) empagliflozin significantly reduced the risk of …
Blinded withdrawal of long-term randomized treatment with empagliflozin or placebo in patients with heart failure
BACKGROUND: It is not known whether the benefits of sodium-glucose cotransporter 2
inhibitors in heart failure persist after years of therapy. METHODS: In the EMPEROR …
inhibitors in heart failure persist after years of therapy. METHODS: In the EMPEROR …
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