[HTML][HTML] Protective and pathologic immune responses in human tegumentary leishmaniasis

LP Carvalho, S Passos, A Schriefer… - Frontiers in …, 2012 - frontiersin.org
Studies in the recent years have advanced the knowledge of how host and parasite factors
contribute to the pathogenesis of human tegumentary leishmaniasis. Polymorphism within …

[HTML][HTML] Cutaneous leishmaniasis: immune responses in protection and pathogenesis

P Scott, FO Novais - Nature Reviews Immunology, 2016 - nature.com
Cutaneous leishmaniasis is a major public health problem and causes a range of diseases
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …

Cutaneous leishmaniasis: the complexity of host's effective immune response against a polymorphic parasitic disease

Á Gabriel, A Valério-Bolas… - Journal of …, 2019 - Wiley Online Library
This review is aimed at providing a comprehensive outline of the immune response
displayed against cutaneous leishmaniasis (CL), the more common zoonotic infection …

[HTML][HTML] Mechanisms of immunopathogenesis in cutaneous leishmaniasis and post kala-azar dermal leishmaniasis (PKDL)

G Volpedo, T Pacheco-Fernandez… - Frontiers in cellular …, 2021 - frontiersin.org
Leishmaniasis is a neglected tropical disease that affects 12 million people worldwide. The
disease has high morbidity and mortality rates and is prevalent in over 80 countries, leaving …

Review on the role of host immune response in protection and immunopathogenesis during cutaneous leishmaniasis infection

T Dubie, Y Mohammed - Journal of immunology research, 2020 - Wiley Online Library
Cutaneous leishmaniasis (CL) is a major public health problem worldwide and spreads to
human via the bite of sand flies during blood meal. Following its inoculation, the …

How to master the host immune system? Leishmania parasites have the solutions!

M Rossi, N Fasel - International immunology, 2018 - academic.oup.com
Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …

Cutaneous leishmaniasis: advances in disease pathogenesis, diagnostics and therapeutics

M Ameen - Clinical and experimental dermatology, 2010 - academic.oup.com
Cutaneous leishmaniasis is one of the most common tropical dermatoses worldwide and is
of major public health importance. It is caused by numerous Leishmania protozoa species …

Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?

D McMahon‐Pratt, J Alexander - Immunological reviews, 2004 - Wiley Online Library
Parasitic protozoa of the genus Leishmania have provided a useful perspective for
immunologists in terms of host defense mechanisms critical for the resolution of infection …

Immune responses during cutaneous and visceral leishmaniasis

L Kedzierski, KJ Evans - Parasitology, 2014 - cambridge.org
Leishmania are protozoan parasites spread by a sandfly insect vector and causing a
spectrum of diseases collectively known as leishmaniasis. The disease is a significant …

Increased expression of proinflammatory cytokines in chronic lesions of human cutaneous leishmaniasis

PC Melby, FJ Andrade-Narvaez, BJ Darnell… - Infection and …, 1994 - Am Soc Microbiol
The nature of the host cellular immune response largely determines the expression of
disease following infection with the intracellular protozoans Leishmania spp. In experimental …