P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis
Abstract Yes-associated protein 1 (YAP1), a key player in the Hippo pathway, has been
shown to play a critical role in tumor progression. However, the role of YAP1 in prostate …
shown to play a critical role in tumor progression. However, the role of YAP1 in prostate …
[HTML][HTML] Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension
Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
The hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells
Yes-associated protein (YAP) is an effector of the Hippo tumor suppressor pathway. The
functional significance of YAP in prostate cancer has remained elusive. In this study, we first …
functional significance of YAP in prostate cancer has remained elusive. In this study, we first …
YAP1 is involved in tumorigenic properties of prostate cancer cells
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
Up regulation of the Hippo signalling effector YAP1 is linked to early biochemical recurrence in prostate cancers
A Marx, A Schumann, D Höflmayer, E Bady… - Scientific Reports, 2020 - nature.com
The transcriptional coactivator YAP1 controls the balance between cell proliferation and
apoptosis. YAP1 overexpression is linked to poor prognosis in many cancer types, yet its …
apoptosis. YAP1 overexpression is linked to poor prognosis in many cancer types, yet its …
PRDM 4 mediates YAP‐induced cell invasion by activating leukocyte‐specific integrin β2 expression
Yes‐associated protein (YAP) is a transcriptional co‐activator and a major effector of the
Hippo pathway that promotes cell proliferation and stemness, while inhibiting apoptosis …
Hippo pathway that promotes cell proliferation and stemness, while inhibiting apoptosis …
The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer
Background After long-term androgen deprivation therapy, 25–30% prostate cancer (PCa)
acquires an aggressive neuroendocrine (NE) phenotype. Dysregulation of YAP1, a key …
acquires an aggressive neuroendocrine (NE) phenotype. Dysregulation of YAP1, a key …
YAP regulates ALDH1A1 expression and stem cell property of bladder cancer cells
AY Zhao, YJ Dai, JF Lian, Y Huang, JG Lin… - OncoTargets and …, 2018 - Taylor & Francis
Background Yes-associated protein (YAP), a key player of the Hippo pathway, has been
identified to have more and more important roles in tumorigenesis and may be an important …
identified to have more and more important roles in tumorigenesis and may be an important …
YAP1 and AR interactions contribute to the switch from androgen-dependent to castration-resistant growth in prostate cancer
The transcriptional co-activator Yes-associated protein 1 (YAP1), a key nuclear effector of
the Hippo pathway, is a potent oncogene, and yet, the interaction between YAP1 and …
the Hippo pathway, is a potent oncogene, and yet, the interaction between YAP1 and …
ARHGAP29 expression may be a novel prognostic factor of cell proliferation and invasion in prostate cancer
K Shimizu, H Matsumoto, H Hirata… - Oncology …, 2020 - spandidos-publications.com
Yes‑associated protein (YAP) is a transcription‑coupling factor that plays a central role in the
Hippo pathway, and its activation regulates cell proliferation and carcinogenesis. YAP …
Hippo pathway, and its activation regulates cell proliferation and carcinogenesis. YAP …
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