Macrophages are central to the initiation and progression of atherosclerosis and thus can be
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …

An impressive body of work has established the current paradigm of atherosclerosis as an
inflammatory process that promotes lesion development and progression. Early atheroma …

Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …

The concept of the involvement of inflammation in the pathogenesis of atherosclerosis has
existed since the 1800s, stemming from sentinel pathologic observations made by Rudolf …

Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …

Introduction• Atherosclerosis‐overview‐General remarks‐Early atherosclerosis‐Exogenous
and/or infectious activators‐Endogenous activators‐Later phases of atherosclerosis• Innate …

Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …

More than 150 years from the initial description of inflammation in atherosclerotic plaques,
randomized clinical trials to test anti-inflammatory therapies in atherosclerosis have recently …

Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

Complex cellular and inflammatory interactions are involved in the progress of vascular
diseases. Endothelial cells, upon exposure to cytokines, undergo profound alterations of …