Sound data support the concept that in atherosclerosis, inflammation and dyslipidemia
intersect each other and that irrespective of the initiator, both participate from the early …

Heart disease and stroke represent the major burden of health worldwide and account for a
staggering 17 million deaths yearly. This pandemic is, in great part preventable through …

The pathobiology of atherosclerosis and its current and potential future treatments are
summarized, with a spotlight on three central cell types involved:(i) endothelial cells …

Coronary artery disease (CAD) and acute myocardial infarction (AMI) are inflammatory
pathologies, involving interleukins (ILs), such as IL-1β, IL-6 and tumor necrosis factor (TNF) …

Inflammation is a well-known pathophysiological factor of atherosclerosis but its therapeutic
targeting has long been ignored. However, recent advances in the understanding of the …

Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

The cellular and extracellular matrix accumulations that comprise the lesions of
atherosclerosis are driven by local release of cytokines at sites of predilection for lesion …

Atherosclerotic cardiovascular disease is a leading cause of death and morbidity globally.
Over the past several years, arterial inflammation has been implicated in the …

Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the
formation of occlusive or rupture-prone lesions in large arteries. Complications of …

Atherosclerosis is a chronic inflammatory disease of the arterial wall that is characterized by
a disturbed equilibrium of immune responses and lipid accumulation, leading to the …