Anti-inflammatory therapies for atherosclerosis

M Bäck, GK Hansson - Nature Reviews Cardiology, 2015 - nature.com
The view of atherosclerosis as an inflammatory disease has emerged from observations of
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …

The interplay of lipids, lipoproteins, and immunity in atherosclerosis

A Pirillo, F Bonacina, GD Norata… - Current atherosclerosis …, 2018 - Springer
Abstract Purpose of Review Atherosclerosis is an inflammatory disorder of the arterial wall,
in which several players contribute to the onset and progression of the disease. Besides the …

Inflammation and the pathogenesis of atherosclerosis

P Libby - Vascular Pharmacology, 2024 - Elsevier
The notion that inflammation contributes to atherosclerosis has now gained considerable
currency. Inflammation participates in atherosclerosis inception, progression, and thrombotic …

Atherosclerosis as an inflammatory disease

A Tuttolomondo, D Di Raimondo… - Current …, 2012 - ingentaconnect.com
In many ways, atherosclerosis is a chronic inflammatory disorder and this issue is confirmed
by recent investigations of that have focused on inflammation, providing new insight into …

Diverse roles of macrophages in atherosclerosis: from inflammatory biology to biomarker discovery

T Gui, A Shimokado, Y Sun, T Akasaka… - Mediators of …, 2012 - Wiley Online Library
Cardiovascular disease, a leading cause of mortality in developed countries, is mainly
caused by atherosclerosis, a chronic inflammatory disease. Macrophages, which …

Macrophages: promising targets for the treatment of atherosclerosis

HM Wilson, RN Barker, LP Erwig - Current vascular …, 2009 - ingentaconnect.com
Atherosclerosis is now recognised as a chronic inflammatory disease occurring within the
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …

New insights and novel therapeutic potentials for macrophages in myocardial infarction

Z Zhang, J Tang, X Cui, B Qin, J Zhang, L Zhang… - Inflammation, 2021 - Springer
Cardiovascular disease (CVD) has long been the leading cause of death worldwide, and
myocardial infarction (MI) accounts for the greatest proportion of CVD. Recent research has …

Key chemokine pathways in atherosclerosis and their therapeutic potential

AB Márquez, EPC van der Vorst, SL Maas - Journal of Clinical Medicine, 2021 - mdpi.com
The search to improve therapies to prevent or treat cardiovascular diseases (CVDs) rages
on, as CVDs remain a leading cause of death worldwide. Here, the main cause of CVDs …

Anti-inflammatory drugs and atherosclerosis

SP Moubayed, TM Heinonen… - Current opinion in …, 2007 - journals.lww.com
Due to the contributory inflammatory pathways in atherosclerosis, the properties of existing
and novel anti-inflammatory agents are being carefully and actively evaluated in …

Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications

E McNeill, KM Channon, DR Greaves - Clinical science, 2010 - portlandpress.com
Atherosclerosis is the pathological process that underlies the development of cardiovascular
disease, a leading cause of mortality. Atherosclerotic plaque formation is driven by the …