Despite great progress being made during the last two decades in cardiovascular disease
prevention, especially by lowering low-density lipoprotein-cholesterol with statins …

The development of atherosclerosis is a complex process whose central elements include
the entrapment of low-density lipoprotein in the vessel wall, its subsequent oxidative …

Epidemiological studies have shown that low levels of plasma high-density lipoprotein
cholesterol (HDL-C) are associated with increased atherosclerotic cardiovascular disease …

High-density lipoprotein (HDL) plays a central role in vascular biology. HDL participates in
multiple pathways that may be involved in the development of atherosclerosis and coronary …

The concentration of high density lipoprotein-cholesterol (HDL-C) has been found
consistently to be a powerful negative predictor of premature coronary heart disease (CHD) …

Numerous epidemiological studies have demonstrated the atheroprotective roles of high
density lipoproteins (HDL), so that HDL is established as an independent negative risk …

The clinical importance of low serum levels of high-density lipoprotein (HDL) cholesterol is
often under-recognized and underappreciated as a risk factor for premature atherosclerosis …

High-density lipoproteins (HDLs) have multiple pleiotropic effects against arteriosclerosis.
Most are independent of the cholesterol mass within HDL particles. Yet, HDL cholesterol …

High-density lipoproteins (HDLs) are heterogeneous particles consisting of a core of neutral
lipids, an envelope of phospholipids, and several proteins. Particle size, lipid and …

Accumulation of cholesterol by macrophages, leading to their transformation into foam cells
is a key event in the initiation of atherosclerosis. As maintenance of cholesterol homeostasis …