Long noncoding RNAs and the regulation of innate immunity and host-virus interactions

M Basavappa, S Cherry… - Journal of leukocyte …, 2019 - academic.oup.com
Immune responses are both pathogen and cell type-specific. The innate arm of immunity is
characterized by rapid intracellular signaling cascades resulting in the production of …

Long noncoding RNAs in host–pathogen interactions

F Agliano, VA Rathinam, AE Medvedev, SK Vanaja… - Trends in …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) are key molecules that regulate gene expression in a
variety of organisms. LncRNAs can drive different transcriptional and post-transcriptional …

Long non-coding RNAs in antiviral immunity

T Vierbuchen, KA Fitzgerald - Seminars in Cell & Developmental Biology, 2021 - Elsevier
Tight regulation of the immune response is fundamental for efficient pathogen clearance and
to prevent excessive inflammation. Long non-coding RNAs (lncRNAs) have emerged as …

Long non-coding RNAs in innate and adaptive immunity

TM Aune, CF Spurlock III - Virus research, 2016 - Elsevier
Long noncoding RNAs (lncRNAs) represent a newly discovered class of regulatory
molecules that impact a variety of biological processes in cells and organ systems. In …

Long non-coding RNAs associated with infection and vaccine-induced immunity

T Lüscher-Dias, IM Conceição, V Schuch… - Essays in …, 2021 - portlandpress.com
The immune system responds to infection or vaccination through a dynamic and complex
process that involves several molecular and cellular factors. Among these factors, long non …

Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation

Z Li, TM Rana - RNA biology, 2014 - Taylor & Francis
The innate immune system is the first line of defense against microbial pathogens, but tight
regulation of gene expression is necessary to prevent the detrimental effects of unrestrained …

Long non-coding RNAs in the regulation of the immune response

JA Heward, MA Lindsay - Trends in immunology, 2014 - cell.com
It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …

Control of immune cell homeostasis and function by lncRNAs

WK Mowel, JJ Kotzin, SJ McCright, VD Neal… - Trends in …, 2018 - cell.com
The immune system is composed of diverse cell types that coordinate responses to infection
and maintain tissue homeostasis. In each of these cells, extracellular cues determine highly …

Long noncoding RNAs in innate immunity

Y Zhang, X Cao - Cellular & molecular immunology, 2016 - nature.com
Long noncoding RNAs (lncRNAs) have been shown to play important roles in immune cell
development and immune responses through different mechanisms, such as dosage …

Long noncoding RNAs in bacterial infection

N Schmerer, LN Schulte - Wiley Interdisciplinary Reviews: RNA, 2021 - Wiley Online Library
Infectious and inflammatory diseases remain major causes of mortality and morbidity
worldwide. To combat bacterial infections, the mammalian immune system employs a …