We previously discovered that mutations of the human FOXP2 gene cause a monogenic
communication disorder, primarily characterized by difficulties in learning to make …

FOXP2 has been identified as a gene related to speech in humans, based on rare mutations
that yield significant impairments in speech at the level of both motor performance and …

Mutations of the human FOXP2 gene have been shown to cause severe difficulties in
learning to make coordinated sequences of articulatory gestures that underlie speech …

Cognitive and motor deficits associated with language and speech are seen in humans
harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are …

Devanna et al.(2014) have demonstrated that FOXP2 mimics, and actually potentiates,
retinoic acid (RA) induction of genes involved in neural differentiation. At the physiological …

The identification of the first gene involved in a speech-language disorder was made
possible through the study of a British multi-generational family (the “KE family”) in whom …

Highlights•Mutations of the FOXP2 gene cause a severe speech and language
disorder.•Mice with Foxp2 disruptions have provided valuable insights into its …

Genetic studies have associated FOXP2 variation with speech and language disorders and
other neurodevelopmental disorders (NDDs) involving pathology of the cortex. In this brain …

The discovery of the FOXP2 transcription factor, and its implication in a rare severe human
speech and language disorder, has led to two decades of empirical studies focused on …

It has been suspected for several decades that genetic factors contribute to speech and
language development/function, based primarily on indirect data from twin studies and …